Balo's concentric sclerosis diagnosed intravitam on brain biopsy

Nandini, Mullatti; Gourie‐Devi, M; Shankar, Susarla Krishna; Ravi, Vignesh

doi:10.1016/0303-8467(93)90106-q

Cited by 13 publications

(8 citation statements)

References 13 publications

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“…Diagnosis can also be established by biopsy. [6] Stadelmann et al, investigated the immunopathology of BCS. [8] Active concentric lesions followed a pattern of demyelination which resembled hypoxia-tissue injury.…”

Section: Discussionmentioning

confidence: 98%

Balò′s concentric sclerosis presenting with benign clinical course and multiple sclerosis-like lesions on magnetic resonance images

Xie

Fan

et al. 2009

Neurol India

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Balò's concentric sclerosis (BCS) is a rare primary demyelinating disease of central nervous system (CNS) and is considered to be a variant of multiple sclerosis (MS). It is characterized by a severe, rapidly evolving course with CNS lesions consisting of concentric rings of demyelination alternating with myelination in the white matter. We report a patient with BCS from mainland China diagnosed on magnetic resonance imaging (MRI) findings. In addition to two contrast enhanced open ring lesions. MRI also showed multiple small white matter lesions in both the hemispheres. The patient had a good response to corticosteroids and had a benign prognosis during a follow-up period of two years.

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Section: Discussionmentioning

confidence: 98%

Balò′s concentric sclerosis presenting with benign clinical course and multiple sclerosis-like lesions on magnetic resonance images

Xie

Fan

et al. 2009

Neurol India

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“…[5][6][7] It shares the basic pathologic similarity to multiple sclerosis, with the exception of an alternating lamellar pattern of demyelinated white matter and well-preserved white matter. [8] BCS and MS like lesions are also known to coexist in same patient. [5] Clinical course of BCS is highly variable.…”

Section: Discussionmentioning

confidence: 99%

“…Most reported cases of BCS have been reported from Asian countries, suggesting the role of genetic and environmental factors. [4][5][6][8][9][10][11] Clinical profile, MRI features, and outcome of patients with BCS reported from India are summarized in Table 1. Coexistence of BCS and oligodendroglioma in the same patient has also been reported.…”

Section: Discussionmentioning

confidence: 99%

Balo′s concentric sclerosis involving bilateral thalami

et al. 2011

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Balo's concentric sclerosis (BCS) is a rare inflammatory demyelinating disease of central nervous system, pathologically characterized by alternate bands of demyelination and preserved myelin tissue. Before the era of magnetic resonance imaging (MRI), most cases of BCS were diagnosed on postmortem examination. MRI allows for noninvasive diagnosis by demonstrating characteristic changes which closely parallels the histopathological features of BCS. We report a case of 26-year-old female with BCS involving bilateral thalami, with typical MRI appearance.

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“…Baló's concentric sclerosis seems to be more frequent in patients of Asian ethnicity [44]. A recent series of seven cases from China suggests that the long-term prognosis (4 to 13.5 years follow-up) may not be always as poor as previously thought and Balo's disease may also co-exist with MS [2].…”

Section: Balo's Diseasementioning

confidence: 99%