Balneophototherapy in vitiligo

Gambichler, Thilo; Maushagen-Schnaas, E.; Müller, Julia; Boonen, H; Schröpl, F

doi:10.3109/09546639709160286

Cited by 3 publications

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“…Accepted for publication March 10, 1998 Many skin diseases are managed succesfully with treatment regimens that combine salt water baths and UV irradiation, especially for heliothalassotherapy and balneophototherapy (1)(2)(3)(4)(5)(6). Therefore, it was of considerable interest to determine how phototherapy is influenced by salt water baths.…”

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Changes of minimal erythema dose after water and salt water baths

Gambichler¹,

Schröpl²

1998

Photoderm Photoimm Photomed

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Knowledge about the influence of salt water baths on UV irradiation, especially balneophototherapy, is incomplete. The aim of this study was to investigate the influence of various concentrated salt solutions on the minimal erythema dose (MED). We determined the MEDdry (UVB) in 24 healthy, previously UV unexposed subjects on the inner forearm. Subjects were divided randomly into two groups of 12. Subsequently, the MEDwet was assessed on each forearm after 30 min tap water or 5% salt water bath (group A), respectively, or after 30 min 10% or 20% salt water bath (group B), respectively. Compared with the MEDdry, a significantly decreased MEDwet, was observed after all exposures (group A==>F = 18.94; P < 0.001; group B==>F = 11.73; P < 0.006). A maximal relative decrease in MEDdry of about 51.4% was observed after the 10% salt water bath. The 5% salt solution caused a modest relative decrease in MEDwet of 23.4%. We observed a markedly increased photosensitivity to UVB after all exposures, without a linear correlation between the MED and the salt water concentration. A determination of MED during balneophototherapy should be carried out after bathing in order to reduce the cumulative UV dose and to prevent acute photodamage.

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confidence: 99%