Balloon cells in malformations of cortical development: friends or foes?
Zili Liu,
Xuefeng Shen,
Kaomin Lin
et al.
Abstract:Balloon cells (BCs) are specific pathological marker of cortical malformations during brain development, often associated with epilepsy and development delay. Although a large number of studies have investigated the role of BCs in these diseases, the specific function of BCs as either epileptogenic or antiepileptic remains controversial. Therefore, we reviewed literatures on BCs, delved into the molecular mechanisms and signaling pathways, and updated their profile in several aspects. Firstly, BCs are heteroge… Show more
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