Balanced propofol sedation administered by nonanesthesiologists: The first Italian experience

Abstract

A balanced sedation protocol provided a minimalization of the dose of propofol needed to target a moderate sedation for colonoscopy, resulting in a high safety profile for non-anesthesiologist propofol sedation.

Safety analysis of endoscopist‐directed propofol sedation: A prospective, national multicenter study of 24 441 patients in German outpatient practices

“…4,6 Several reports worldwide stated that EDP is a safe procedure. 15,19,20,[22][23][24][25][26][27][28][29] Nevertheless, some National Societies of Anaesthesiology have officially and publicly dissociated themselves from the NAAP guidelines, 16 and the Centers for Medicare and Medicaid Services have issued a clarification statement of an interpretive guideline that shut down the practice of EDP sedation in most hospitals in the United States. 18 These policies were pursued without any supporting evidence.…”

A clinical trial comparing propofol versus propofol plus midazolam in diagnostic endoscopy of patients with a low anesthetic risk

“…These evoke a synergetic action, without increasing the side effects and reduce the total required dose of propo-fol (25,26). This protocol, which aims to achieve a moderate-profound sedation level, has been described in the recent medical literature as "balanced propofol sedation" (BPS) (27)(28)(29) and has been compared to propofol administration as the only sedative (29)(30)(31)(32)(33).…”

National Endoscopy Quality Improvement Program Remains Suboptimal in Korea

“…It seems likely that higher participation of endoscopists from primary clinic in that study19 may be a possible explanation for higher preference for propofol use compared with our data. The widespread use of propofol for gastrointestinal endoscopy has also been documented in several European countries 20,21. As the characteristics of propofol include a rapid onset of action with a short-term effect, a shorter recovery time, and greater patient and endoscopist satisfaction,22 propofol use may be preferred by endoscopists practicing in primary clinic setting 19.…”