Bakuchiol derivatives from the leaves of Psoralea glandulosa

Labbé, Cecilia; Faini, Francesca; Coll, Joseph; Connolly, Joseph D.

doi:10.1016/0031-9422(96)00144-6

Cited by 63 publications

(44 citation statements)

References 9 publications

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“…An extensive study of the NMR data, including HMQC, HMBC and H, H COSY experiments, confirmed unambiguously the structure of suggested coumarin. On the basis of the close agreement of their physical and spectral data with those already published, compounds 3, 4, 5, 6, 7, 8, 9 and 10 were found to be identical with those of the known compounds, isosamidin, 14) laserpitin, 14) pteryxin, 16) isolaserpitin, 14) cis-khellactone, 15) angelicin, 19) genkwanin 20) and salvigenin, 20) respectively.…”

Section: Resultssupporting

confidence: 74%

Two New Coumarins from the Chloroform Extract of Angelica urumiensis from Iran

et al. 2010

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Section: Resultssupporting

confidence: 74%

Two New Coumarins from the Chloroform Extract of Angelica urumiensis from Iran

et al. 2010

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“…Among them, the following 15 were identified as known compounds by comparison of their spectral data with those in the literature: corylifol C (3) [5], bavachinin (4) [11], bavachin (5) [12], neobavaisoflavone (6) [11], corylin (7) [13], corylifol A (8) [5], 8-prenyldaidzin (9) [14,15], isobavachalcone (10) [11], corylifol B (11) [5], bakuchiol (12) (16) [18], and isopsoralen (17) [19] (Figure 1). The remaining two compounds were regarded as novel and named bakuisoflavone (1) and bakuflavanone (2) (Figure 1).…”

Section: Resultsmentioning

confidence: 99%

“…These results shown in the present study suggested that the HPLC method can be utilized for quality control with respect to the antibacterial resource. (4) 5.03 ± 0.100 Bavachin (5) 1.80 ± 0.059 Neobavaisoflavone (6) 2.33 ± 0.054 Corylifol A (8) 1.86 ± 0.046 Isobavachalcone (10) 3.14 ± 0.111 Corylifol B (11) 1.81 ± 0.121 Bakuchiol (12) 16.49 ± 0.455 Psoralen (16) 1.76 ± 0.052 Isopsoralen (17) 1.26 ± 0.071 a The value was given as the mean ± standard deviation (SD) based on the triplicate experiments. The indicated number of each peak is corresponding to the compound number displayed in Figure 1.…”

Section: Quantitative Analysis Of the Major Constituents In P Corylimentioning

confidence: 99%

Constituents of Psoralea corylifolia Fruits and Their Effects on Methicillin-Resistant Staphylococcus aureus

et al. 2015

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Abstract:Two new flavonoids, bakuisoflavone (1) and bakuflavanone (2), together with 15 known compounds, were isolated from the fruits of Psoralea corylifolia, and their structures were characterized by spectroscopic data. The effects of the isolated compounds on methicillin-resistant Staphylococcus aureus were also examined. We found that two compounds, isobavachalcone (10) and bakuchiol (12), showed noticeable antibacterial effects on the MRSA strains examined. Quantitation of the major constituents, including anti-MRSA constituents, was then performed. The results showed individual contents of 1.26%-16.49% (w/w) among the examined compounds in the ethyl acetate extract from P. corylifolia fruits.

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“…The compounds were identified by comparison of their spectral data (UV, ½ D , MS, and NMR) with data previously reported. [11][12][13][14][15][16] Next, compounds 1-3 were examined with regard to their ability to suppress melanin biosynthesis in B16 cells. The addition of the isolated compounds to the cells prior to stimulation with 100 nM -MSH markedly decreased the production of melanin, in a dose-dependent manner (Fig.…”

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confidence: 99%