Bakterielle Koxitis durch Salmonella enteritidis

Sarkar, Michael R.; Rose, Carsten; Wachter, N; Mohr, W; Kinzl, L.

doi:10.1007/s001130050511

Cited by 3 publications

(3 citation statements)

References 19 publications

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“…The Girdlestone-hip (excision arthroplasty of the femoral head) with the subsequent insertion of local antibiotic-impregnated media is still counting among the standard treatment options of the destructive, bacterial coxitis 16-18, 20. It is also performed in the treatment of the septic femoral neck pseudarthrosis.…”

Section: Discussionmentioning

confidence: 99%

“…It is also performed in the treatment of the septic femoral neck pseudarthrosis. Frequently, pathogen organisms as tuberculosis and salmonella bacteria can be isolated from such infections 6, 13, 18, 20, 23. With regard to these organisms and the increasing ratio of multiresistant bacteria 11-12, 25 a local antibiosis has become difficult to apply.…”

Section: Discussionmentioning

confidence: 99%

“…Thus, in these cases a two-stage treatment is often required. Beyond the obligate systemic antibiosis, the common procedure includes an excision arthroplasty of the femoral head (Girdlestone-hip) with a simultaneous insertion of commercial antibiotic-loaded device (beads or collagen sponges) 16-18, 20. In case of multimicrobial infections, these commercial antibiotic-impregnated media cannot provide frequently a sufficient antibiotic therapy.…”

Section: Introductionmentioning

confidence: 99%

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Treatment of proximal femur infections with antibiotic-loaded cement spacers

Kelm¹,

Bohrer²,

Schmitt³

et al. 2009

Int. J. Med. Sci.

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In case of periprosthetic hip infections the implantation of antibiotic-loaded PMMA spacers is accepted for an adequate treatment option. Although their indication for the treatment of destructive, bacterial infections of the proximal femur would make sense, literature data are scarce. Hence, the aim of this study was to evaluate the efficacy of antibiotic-impregnated spacers in the treatment of proximal femur infections.In 10 consecutive patients (5 M/ 5 F, mean age 66 y.) with bacterial proximal femur infections, a femoral head/neck resection was prospectively performed with a subsequent implantation of an antibiotic-loaded spacer. The joint-specific outcome was evaluated by the Merle d´Aubigne and the Mayo hip score, the general outcome by SF-36. The time periods were divided into “infection situation”, “between stages” and meanly 1 year “after prosthesis implantation”.The spacers were meanly implanted over 90 [155-744] days. In all cases an infection eradication could be achieved. After infection eradication, a prosthesis implantation was performed in 8 cases. The general scores showed significant increases at each time period. With regard to the dimension “pain”, both scores demonstrated a significant increase between “infection situation” and “between stages”, but no significance between “between stages” and “after prosthesis implantation”.Spacers could be indicated in the treatment of proximal femur infections. Besides an infection eradication, a pain reduction is also possible.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Treatment of proximal femur infections with antibiotic-loaded cement spacers

Kelm¹,

Bohrer²,

Schmitt³

et al. 2009

Int. J. Med. Sci.

View full text Add to dashboard Cite

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Entzündungen bekannter Ätiologie

Mohr

2000

Gelenkpathologie

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Salmonella enteritidis causing brain abscess and coxitis following intracranial surgery

Schröder

Palkovic

Kipp

et al. 2003

Acta Neurochirurgica

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We report the case of a 46-year-old woman who underwent surgery for an adamantinous craniopharyngeoma (WHO grade I). The postoperative course, during which the patient received 16 mg/day of dexamethasone, was initially uneventful. After a fortnight the patient developed infectious signs and an intracranial abscess at the operation site with simultaneous purulent coxitis. Both the intracranial abscess and the coxitis were evacuated and drained. In tissue samples and pus obtained during re-craniotomy and during surgery on the hip, Salmonella enteritidis was detected by cultivation. Salmonella enteritidis was also isolated from several stool specimens. There was no known salmonellosis in the patient's medical history. She recovered as a result of antibiotic treatment with ciprofloxacin and chloramphenicol. The intracranial abscess healed without leaving any neurological deficit. Unfortunately the left hip subsequently required further surgery, culminating in removal of the entire femoral head. Prosthetic replacement could not yet be performed due to the recurrent septic course of the hip. Our case illustrates a serious complication with presumed haematogenous spread of the infection from a pre-existing asymptomatic and unknown colon infection. The immunosuppressive effect of corticosteroids in the treatment of the brain neoplasm might have been a contributing factor to the sudden exacerbation of the latent infection.

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Bakterielle Koxitis durch Salmonella enteritidis

Cited by 3 publications

References 19 publications

Treatment of proximal femur infections with antibiotic-loaded cement spacers

Treatment of proximal femur infections with antibiotic-loaded cement spacers

Entzündungen bekannter Ätiologie

Salmonella enteritidis causing brain abscess and coxitis following intracranial surgery

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