2024
DOI: 10.1101/2024.04.08.588634
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BAITSAO: Building A Foundation Model for Drug Synergy Analysis Powered by Language Models

Tianyu Liu,
Tinyi Chu,
Xiao Luo
et al.

Abstract: Drug synergy prediction is a challenging and important task in the treatment of complex diseases including cancer. In this manuscript, we present a novel Foundation Model, known as BAITSAO, for tasks related to drug synergy prediction with a unified pipeline to handle different datasets. We construct the training datasets for BAITSAO based on the context-enriched embeddings from Large Language Models for the initial representation of drugs and cell lines. After demonstrating the relevance of these embeddings, … Show more

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