Baijiu vinasse as a new source of bioactive peptides with antioxidant and anti-inflammatory activity

Lin, Peng; Kong, Xiaoyong; Wang, Zongmin; Ai‐lati, Aisikaer; Ji, Zhongwei; Mao, Jian

doi:10.1016/j.foodchem.2020.128159

Cited by 45 publications

(25 citation statements)

References 37 publications

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“…Numerous researches have been reported on isolation, identification, antioxidant activity and other biological efficacy of bioactive peptides from different sources of natural protein hydrolysates (Li et al ., 2007; Zhu et al ., 2008). Food crops like baijiu vinasse (Peng et al ., 2021), selenium‐enriched rice protein hydrolysates (Fang et al ., 2019), corn (Jin et al ., 2016), rice (Yan et al ., 2015), green tender sorghum (Agrawal et al ., 2017) and pearl millets (Agrawal et al ., 2016), food grains like soybean‐based infant formulas (Puchalska et al ., 2014) and nuts like chestnut (Feng et al ., 2018) and pine nut (Yang et al ., 2017), have been shown to contain antioxidant peptides.…”

Section: Introductionmentioning

confidence: 99%

Characterisation of antioxidant peptides from enzymatic hydrolysate of golden melon seeds protein

Chen

Zhu

et al. 2021

Int J of Food Sci Tech

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Summary The purpose of present research was to study novel antioxidant peptides from Golden melon seeds. Alkaline protease was used to hydrolyse the Golden melon seeds protein to obtain the hydrolysed peptides. These antioxidant peptides were purified and identified by ultrafiltration, gel filtration chromatography and RP‐HPLC‐ESI‐MS/MS. Results showed that the peptide fraction (GMSHp3) with molecular weight (MW) <3 kDa obtained by ultrafiltration had the highest antioxidant capacity. This fraction was further purified via gel filtration chromatography into six sub‐fractions, among which GMSHp3‐3 exhibited the highest hydroxyl radical scavenging effect. Fraction GMSHp3‐3 was further purified via RP‐HPLC‐ESI‐MS/MS and sequenced as six potential antioxidant peptides with amino acids sequences of RMSFPVMCRN, LMRVLAQLG, ALAPLVALPAA, LVGKPAPD, LPAAHKA and AHAAGYGG, among which LMRVLAQLG, LPAAHKA and AHAAGYGG possessed effective ferric reducing power. These results indicated that novel antioxidant peptides from golden melon seeds protein hydrolysates might be potential antioxidant source of functional foods or nutraceutical supplements.

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Section: Introductionmentioning

confidence: 99%

Characterisation of antioxidant peptides from enzymatic hydrolysate of golden melon seeds protein

Chen

Zhu

et al. 2021

Int J of Food Sci Tech

View full text Add to dashboard Cite

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“…It is known that antioxidant properties of proteins and peptides are due to complex interactions between their ability to inactivate reactive oxygen species, scavenge free radicals, chelate prooxidative transition metals, enzymatically eliminate specific oxidants, and alter the physical properties of food systems in a way that separates reactive species. In this sense, changes in the amino acid composition, length of the peptide chain and three-dimensional structure of proteins can interfere on their ability to act as antioxidants ( Peng, Kong, Wang, Ai-lati, Ji, & Mao, 2021 ). It is possible that during hardening, the spatial structure of the amino acids in the protein/peptide sequence might be changed, interfering with their hydrogen donor ability and, consequently, reducing their DPPH • radical scavenging activity.…”

Section: Resultsmentioning

confidence: 99%

Effect of extrusion and autoclaving on the biological potential of proteins and naturally-occurring peptides from common beans: Antioxidant and vasorelaxant properties

et al. 2022

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“…In the current study, results showed that, although all the AVHs exhibited some DPPH scavenging activity, the activities of peptide fractions with MWs <1 kDa were significantly stronger than those of peptides with larger MWs ( P < 0.01), while no significant differences were observed among the peptide components with MWs >1 kDa in the AVHs of all the proteases (except Alp). This may be due to the fact that small molecular peptides have low steric hindrance and are more likely to be in contact with free radicals to exert their antioxidant effects (Peng et al ., 2021).…”

Section: Discussionmentioning

confidence: 99%

Fractionation and purification of antioxidant peptides from abalone viscera by a combination of Sephadex G‐15 and Toyopearl HW‐40F chromatography

Yang

et al. 2021

Int J of Food Sci Tech

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Abalone viscera, a protein-rich by-products from the abalone processing industry, are normally discarded as wastes. In the present study, four different proteases were used to hydrolyse abalone viscera to prepare highactivity antioxidant peptides, and their hydrolysis effects were compared. Although the hydrolytic abilities of papain and trypsin were inferior to the alcalase and neutrase, their use resulted in significantly (P < 0.05) higher scavenging activities for DPPH. The hydrolysates mainly consisted of peptides with a molecular weight <3 kDa, and the fractionation was achieved using a combination of Sephadex G-15 and Toyopearl HW-40F gel filtration chromatography, which overcomes the disadvantages of traditional membrane separation technology in fractionating peptides with relatively similar molecular weight distribution. The DPPH scavenging activities of the components containing peptides <1 kDa (fractions E) were significantly (P < 0.01) higher than those containing peptides >1 kDa. The different fractions E were further purified by reversed-phase high-performance liquid chromatography, and a total of 16 target peptides, containing 4-8 amino acids, enriched in hydrophobic amino acids and C-terminal Arg, with molecular weights ranging from 500 to 850 Da, were identified.

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Baijiu vinasse as a new source of bioactive peptides with antioxidant and anti-inflammatory activity

Cited by 45 publications

References 37 publications

Characterisation of antioxidant peptides from enzymatic hydrolysate of golden melon seeds protein

Characterisation of antioxidant peptides from enzymatic hydrolysate of golden melon seeds protein

Effect of extrusion and autoclaving on the biological potential of proteins and naturally-occurring peptides from common beans: Antioxidant and vasorelaxant properties

Fractionation and purification of antioxidant peptides from abalone viscera by a combination of Sephadex G‐15 and Toyopearl HW‐40F chromatography

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