Baicalin enhances proliferation and reduces inflammatory-oxidative stress effect in H2O2-induced granulosa cells apoptosis via USP48 protein regulation
Jun Chen,
Chuhua Lin,
Xiurong Huang
et al.
Abstract:Background
Oxidative stress and inflammation can lead to apoptosis of ovarian granulosa cells (GCs), resulting in ovulation disorders and infertility. Baicalin (BAI) promotes cell proliferation and reduces inflammation and oxidative stress. However, the mechanisms by which BAI treatment affects oxidative stress and inflammation in GCs remain incompletely understood.
Methods
KGN cells were treated with hydrogen peroxide (H2O2) to analyze the effect … Show more
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