Baduanjin exercise: A potential promising therapy toward osteoporosis

Abstract

PurposeBaduanjin (BDJ) exercise is a traditional exercise that combines breathing, body movement, meditation and awareness to help delay the onset and progression of senile degenerative musculoskeletal diseases, such as osteoporosis (OP). The aim of this meta-analysis is to evaluate the efficacy of BDJ exercise, and preliminarily infer its effective mechanism in the treatment of OP.MethodsWe identified relevant randomized controlled trials (RCTs) through eight databases, and compared BDJ exercise with the control groups (including blank control and conventional treatment intervention). The main outcome measure was bone mineral density (BMD), the additional outcome measures were visual analogue scale (VAS), Berg balance scale (BBS), serum Calcium (Ca), serum Phosphorus (P), serum Alkaline phosphatase (ALP), and serum bone gla protein (BGP). Meta-analysis and trial sequence analysis (TSA) were performed using RevMan 5.4, Stata 16.0, and TSA 0.9.ResultsIn total, 13 RCTs involving 919 patients were included in the analysis. For postmenopausal osteoporosis, BDJ exercise alone and BDJ exercise combined with conventional treatment can improve the BMD of lumbar spine. BDJ exercise alone can influence serum Ca and ALP. BDJ exercise combined with conventional treatment can improve balance (BBS) and influence serum BGP. For senile osteoporosis, BDJ exercise alone and BDJ exercise combined with conventional treatment can improve balance (BBS). BDJ exercise combined with conventional treatment can improve the BMD of hip and pain relieve (VAS). For primary osteoporosis, BDJ exercise combined with conventional treatment can improve the BMD of lumbar spine and femoral neck.ConclusionBaduanjin exercise may be beneficial to improve BMD, relieve pain, improve balance ability, influence serum BGP and serum ALP in patients with OP, but differences occur due to various types of OP. Due to the low quality of research on the efficacy and mechanism of BDJ exercise in the treatment of OP, high-quality evidence-based research is still needed to provide reliable supporting evidence.Systematic Review Registration[http://www.crd.york.ac.uk/PROSPERO], identifier [CRD42022329022].

Eupatilin ameliorates postmenopausal osteoporosis via elevating microRNA‐211‐5p and repressing JAK2/STAT3 pathway

“…45 Ca and phosphorus in the blood reflect the physical structure of the bones. 46 Ca is an important mineral in the human body, of which 99% is found in the bones and teeth, and the remaining 1% is distributed in the blood, nerves, and various soft tissues. 47 Properly increased Ca content is beneficial to calcium deposition in bone, while excessively increased Ca content may be deposited in the soft tissues such as blood vessels.…”

“…ALP is a measure of bone formation and transformation, since release into the blood disrupts estrogen production, whereas elevated serum ALP activity reflects the activity of bone cell metabolic processes 45 . Ca and phosphorus in the blood reflect the physical structure of the bones 46 . Ca is an important mineral in the human body, of which 99% is found in the bones and teeth, and the remaining 1% is distributed in the blood, nerves, and various soft tissues 47 .…”

Perceptions Toward Exercise or Mindful Exercise Participation Among Patients With Primary Osteoporosis: A Qualitative Study

“…Researchers have applied Yoga, Pilates, Tai Chi, and Ba Duan Jin to patients with osteoporosis and have obtained various results. Although many studies have reported the effectiveness of pain relief (Oksuz & Unal, 2017; Sun et al, 2021), there were still negative results reported by researchers (Grahn Kronhed et al, 2020). Exercising the wrong way could cause adverse consequences (Sluka et al, 2018).…”

The effect of Baduanjin exercise on health-related physical fitness of college students: A randomized controlled trial

“…Then take the lumbar spine as the axis to drive their four limbs movement, while alternately change the muscle tension and relaxation at different parts of the body. At same time, the mind, body, and breath are required to be smooth and unstrained ( 26 ). Numerous studies have already proven that Baduanjin is a popular community exercise to promote health in China, and especially suitable for older adults ( 13 , 17 , 27 ).…”