Bacteriophage-Based Biosensors: Detection of Bacteria and Beyond

Paczesny, Jan; Wdowiak, Mateusz; Ochirbat, Enkhlin

doi:10.1007/978-981-16-9190-4_20

Cited by 3 publications

(1 citation statement)

References 168 publications

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“…Phages only infect specific bacterial strains, so phage-originated or phagemixture recognition proteins can be designed in order to sense the target bacterial spectrum in their natural state selectively 88 . A single phage can target a specific bacterial species or even a strain, so a phage that recognizes the target bacteria can always be found 89 Whole-phage probes, nucleic acid probes, phagedisplay peptides, antibodies-based probes, and receptor-binding proteins from phages have all been used in order to detect infections on biosensor surfaces 90 . Bioassays and biosensors based on phages have been developed using surface plasmon resonance, magnetoelastic platform, quartz crystal microbalance, and electrochemical techniques.…”

Section: Potential Biodetectorsmentioning

confidence: 99%

Positive and negative aspects of bacteriophages and their immense role in the food chain

Ranveer,

Dasriya,

Ahmad

et al. 2024

npj Sci Food

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Bacteriophages infect and replicate inside a bacterial host as well as serve as natural bio-control agents. Phages were once viewed as nuisances that caused fermentation failures with cheese-making and other industrial processes, which lead to economic losses, but phages are now increasingly being observed as being promising antimicrobials that can fight against spoilage and pathogenic bacteria. Pathogen-free meals that fulfil industry requirements without synthetic additives are always in demand in the food sector. This study introduces the readers to the history, sources, and biology of bacteriophages, which include their host ranges, absorption mechanisms, lytic profiles, lysogenic profiles, and the influence of external factors on the growth of phages. Phages and their derivatives have emerged as antimicrobial agents, biodetectors, and biofilm controllers, which have been comprehensively discussed in addition to their potential applications in the food and gastrointestinal tract, and they are a feasible and safe option for preventing, treating, and/or eradicating contaminants in various foods and food processing environments. Furthermore, phages and phage-derived lytic proteins can be considered potential antimicrobials in the traditional farm-to-fork context, which include phage-based mixtures and commercially available phage products. This paper concludes with some potential safety concerns that need to be addressed to enable bacteriophage use efficiently.

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Section: Potential Biodetectorsmentioning

confidence: 99%

Positive and negative aspects of bacteriophages and their immense role in the food chain

Ranveer,

Dasriya,

Ahmad

et al. 2024

npj Sci Food

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Nanotechnology for bacteriophages, bacteriophages for nanotechnology

Raza,

Paczesny

2023

Nanoscience

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The first uses of nanotechnology were incidental, like in the cases of the first human-made nanostructures dating back to 600 BC when coatings of carbon nanotubes were made in ancient pottery shards or the famous 4th-century Lycurgus cup. Now, we carefully design functional nanostructures. These designs are often bio-inspired or composed of bio-parts. We are aiming to create life-like systems. The conflict will remain in defining the stage when such systems could be considered living. A similar dilemma is persistent in the realm of viruses, which are considered living or not, depending on the perception. This chapter describes the mutual relation between nanotechnology and bacteriophages (phages for short). Bacteriophages are viruses that infect bacteria and use bacterial cellular machinery to replicate. Phages are often seen as bio-nanomaterials with high specificity, uniform structure, and easy replication. Over the years, phages and nanomaterials have been helpful to each other in enhancing their applications. In different approaches, nano-phage particles work in synergy to derive better results. This chapter is divided into two major sections: ‘bacteriophages for nanotechnology’ and ‘nanotechnology for bacteriophages’.

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Perceptions of Infection Control Among Nurses Regarding Barriers: A Qualitative Study

Shoukat

Ali

Aziz

2023

PJHS

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Infection in healthcare facilities is an alarming public health problem in most growing countries. Hospital infections are the most significant worldwide complication of healthcare delivery. Objectives: To acquire a deeper understanding of infection control nurses' perspectives on the barriers regarding the infection control practices at the tertiary care hospitals Lahore. Methods: A qualitative exploratory research approach was utilized. Data was collected from the infection control nurses. Semi-structured interviews were used to collect the data from the 10 study participants through purposive sampling technique. Each interview was transcribed. The data were manually analyzed before being processed by NVIVO. Results: A thematic analysis was conducted to determine the themes and sub themes through Braun and Clark's (2006) concept of thematic analysis. The researcher identified three major themes and few minor. The major themes were organization related barriers, health care workers related barriers and patients and family related barriers. Organization lack of facilities was among the top barriers to infection prevention and control. Conclusions: Most of the participants had good and enough information regarding the infection prevention and control programs, but it doesn’t mean that these activities and implementations will be practiced in routine manners. Three major themes with different barriers were identified. Themes well explained regarding barriers in implementing infection control practices in both public and private hospitals.

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Bacteriophage-Based Biosensors: Detection of Bacteria and Beyond

Cited by 3 publications

References 168 publications

Positive and negative aspects of bacteriophages and their immense role in the food chain

Positive and negative aspects of bacteriophages and their immense role in the food chain

Nanotechnology for bacteriophages, bacteriophages for nanotechnology

Perceptions of Infection Control Among Nurses Regarding Barriers: A Qualitative Study

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