Bacteriological study and antibiotic sensitivity profile in patients with ear discharge visiting ENT OPD at tertiary care center

Abstract

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">Otitis media (OM) is a big menace in countries like India. Chronic suppurative otitis media (CSOM) is chronic inflammation of middle ear, which affects the tympanic membrane, middle ear mucosa and other middle ear structures characterised by the presence of persistent perforation or persistent mucoid or muco-purulent discharge for at least 8 weeks. Variety of organisms founds in patients suffering from chronic otitis media like, <em>Pseudomonas</em>, <em>Staphylococcus aureus</em>, <em>Proteus mirabilis</em>, <em>Klebsiella pneumonia</em> and <em>Escherichia coli</em> found. The pattern of organisms varies in different geographical areas. The objectives of the study were to isolate bacteria from patients with ear discharge, to find out antibiotic sensitivity of isolated organisms</span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">This is an observational cross sectional study done in the OPD department of otorhinolaryngology, at P.D.U medical college and hospital, Rajkot, for a period of six months from January 2017 to June 2017. A total number 200 patients of both gender between 5 to 74 years who visited the OPD department of otorhinolaryngology with chronic ear discharge taken for study. </span></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">Out of 200 patients of 5-74 years with chronic suppurative otitis media were examined and out of this Hundred and twelve (54%) of the patients were males with mean age of 33.44. <em>Pseudomonas aeruginosa</em> was the commonest identified organisms the sensitivity pattern highly favoured Pipercillin, Amikacin and Polymyxin B, Cefoparazone. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">Chronic otitis media is more prevalent in males than females. Commonest organisms found were <em>Pseudomonas aeruginosa</em> followed by <em>Staphylococcus aureus. </em>Piperacillin, Amikacin, Gentamicin, Polymyxin B and Cefoperazone were found most effective agents against <em>Pseudomonas aeruginosa</em>.</span></p>

Study of bacterial pathogens causing chronic suppurative otitis media and the antibiotic susceptibility pattern of the isolates at a tertiary care centre in Kochi

“…This was similar to the findings of Patel et al and Rangaiah et al in Gujarat and Karnataka respectively. 18,19 The increased incidence in this age group may be due to increased environmental and occupational exposure in this age group. In our study population, 52 were males and 48 were females, indicating a slight male predominance.…”

“…This was in agreement with some other studies while contradicting certain other studies. [18][19][20][21] The majority i.e.76 patients presented with right sided ear discharge, whereas 24 presented with left ear discharge. There were no cases of bilateral ear discharge.…”

“…In similar studies by Patel et al and Nagraj et al, Pseudomonas was found to be the commonest isolate from cases of CSOM. 18,22 However studies by Prakash et al and Sharma et al demonstrated a predominant growth of Staphylococcus aureus. 20,21 This could be due to geographical variations and the different population studied.…”

“…Pseudomonas aeruginosa being ubiquitous in our physical environment with a predilection for moist areas is commonly isolated in CSOM. 18,21 The increased isolation of Pseudomonas aeruginosa has several implications since it is an important cause of hospital acquired infections. Moreover, Pseudomonas aeruginosa is difficult to treat since it has no particular environmental or nutritional requirements to grow and is highly resistant to antibiotics.…”

“…The sensitivity to gentamicin, amikacin, cotrimoxazole, clindamycin was high, whereas it was low for penicillin, erythromycin, and ciprofloxacin, this was similar to the finding of other studies. 18,26…”