Bacteriological Profile of Infected Surgical Sites in Jos, Nigeria

Abstract

The often-high mortality and morbidity rates of surgical site infections are the concern of most health practitioners including administrators globally. The need to know the bacterial agents responsible and their treatability to common antibiotics was the main thrust of this study. Two hundred surgical site swabs were collected from two hospitals and investigated. The swabs were cultured and organisms identified according to standard procedures. A prevalence rate of 31.5 % was obtained from the surgical sites investigated. Direct gram staining gave a greater recovery rate of incriminated organisms than cultural methods. Staphylococcus aureus was the most encountered pathogen with 13.0 % prevalence rate followed by Pseudomonas aeruginosa (6.5 %), Proteus mirabilis (6.0 %) and Klebsiella aerogenes (4.0 %).The least encountered pathogens were Beta-haemolytic streptococci and Escherichia coli with prevalence rates of 1.0 % each. Statistically, chi square analysis showed that there was no significant difference in the number of isolates from the two health facilities at 99 % confidence limit. Susceptibility of isolates was more with the aminoglycosides than with the penicillins. This study has thus revealed that some hospitals are not doing enough to stem the tide of surgical site infections.

Phenotypic detection of multi-drug resistant MBL-producing Gram-negative bacteria isolated from clinical samples of patients in hospitals in Akwa Ibom State, Nigeria

“…There are currently no clinically available inhibitors to block MBL action. Thus, the dissemination of the genes encoding these enzymes remains an important cause of resistance in Gram-negative bacteria and a serious public health concern (Chollom et al, 2012). The genes that code for these resistances are carried on mobile genetic elements such as plasmids, chromosomes and transposons, and have been shown to be either transported by integrons or packaged by gene cassettes (Sharma et al, 2013).…”

“…Metallo beta-lactamase-producing Gram-negative bacteria have been reported as important cause of nosocomial and community-acquired infections including urinary tract infections (UTIs), surgical wound infections, pyogenic infections, cystic fibrosis, septicemia, pneumonia, meningitis, bacteremia, endocarditis, osteomyelitis, pyelonephritis, enterocolotis, puerperal sepsis, peritonitis and soft tissue infection among others (Samuel et al, 2010;Chollom et al, 2012). The prevalence rates of these infections have been reported within and outside the country by many researchers: 11.23% by Ajuba et al (2020) in Anambra, 8.5% by Oduyebo et al (2016) in Lagos, 8.6% by Abdullahi et al (2017) in Kano and 36.1% by Adam and Elhag (2018) in Sudan.…”