Bacteriological profile of community-acquired pyodermas with special reference to methicillin resistant Staphylococcus aureus

Thind, Parveen; Prakash, S Krishna; Wadhwa, Anupriya; Garg, VK; Pati, Binod Kumar

doi:10.4103/0378-6323.69064

Cited by 14 publications

(12 citation statements)

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“…[91011121314151617181920] Multi-resistant enterobacteriaceae due to the production of extended spectrum β-lactamases (ESBL) have become very common in India. [1112] In addition, various studies in South India highlighted the drug resistance pattern like multidrug resistant Extended-Spectrum β-Lactamase Producing Klebsiella pneumoniae , Ciprofloxacin resistant Salmonella enteric serovar Typhi , emergence of vancomycin-intermediate staphylococci , fluoroquinolone resistance among Salmonella enteric serovar Paratyphi A, Pseudomonas aeruginosa and Acinetobacter baumannii resistant to ceftazidime, cefepime and ciprofloxacin.…”

Section: Methodsmentioning

confidence: 99%

“…These isolates of CA-MRSA are not multidrug resistant unlike the hospital acquired MRSA, in that way being a boon to the clinician as it keeps the treatment options wide. [18] There is not much data on high incidence of vancomycin resistant enterococci (VRE) in India. However, reduced susceptibility to vancomycin was observed in a study in about 12% of the isolates of Enterococcus fecalis .…”

Section: Methodsmentioning

confidence: 99%

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Antimicrobial resistance in India: A review

Kumar¹,

Adithan²,

Harish³

et al. 2013

J Nat Sc Biol Med

182

102

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Antimicrobial resistance is an important concern for the public health authorities at global level. However, in developing countries like India, recent hospital and some community based data showed increase in burden of antimicrobial resistance. Research related to antimicrobial use, determinants and development of antimicrobial resistance, regional variation and interventional strategies according to the existing health care situation in each country is a big challenge. This paper discusses the situational analysis of antimicrobial resistance with respect to its problem, determinants and challenges ahead with strategies required in future to reduce the burden in India. Recent data from Google search, Medline and other sources were collected which was reviewed and analyzed by the authors. Hospital based studies showed higher and varied spectrum of resistance in different regions while there are limited number of community based studies at country level. There exists lacunae in the structure and functioning of public health care delivery system with regard to quantification of the problem and various determining factors related to antimicrobial resistance. There is an urgent need to develop and strengthen antimicrobial policy, standard treatment guidelines, national plan for containment of AMR and research related to public health aspects of AMR at community and hospital level in India.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Antimicrobial resistance in India: A review

Kumar¹,

Adithan²,

Harish³

et al. 2013

J Nat Sc Biol Med

182

102

View full text Add to dashboard Cite

show abstract

“…[10] Recently, many authors also reported pyoderma to be more common in the first decade of life. [1112]…”

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confidence: 99%

Clinical and bacteriological aspects of pyoderma

et al. 2012

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“…[14] Resistance to penicillin was noted within 4 years of introduction of penicillin and was due to the production of enzymes called β-lactamase (penicillinase) by previously susceptible bacteria. [1] Methicillin, the first β-lactamase stable semi-synthetic penicillin was introduced in 1960. [8] Resistance was detected within a year of its introduction.…”

Section: Discussionmentioning

confidence: 99%

“…Staphylococcus aureus and β-hemolytic streptococcus are the most common etiological agents. [12] Pyoderma, commonly caused by S. aureus , accounts for up to 17% of clinical visits in dermatological practice. [3] S. aureus often colonizes hospitalized as well as healthy people without any sign of infection.…”

Section: Introductionmentioning

confidence: 99%

The clinical spectrum and antibiotic sensitivity patterns of staphylococcal pyodermas in the community and hospital

et al. 2014

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Context:The uncontrolled use of antibiotics has resulted in a relentless spread of multiresistant strains of Staphylococcus aureus. There are studies conducted in medical colleges in Chandigarh, Chennai, Mumbai and Vellore comparing pyodermas in the community and hospital setting based on clinical and bacteriological parameters.Aims:This study, conducted over 1½ years from March 2009 to August 2010, aimed at analyzing the clinical spectrum and antibiotic sensitivity pattern of community and hospital-associated (HA) staphylococcal pyoderma. It also assessed the prevalence of methicillin-resistant S. aureus (MRSA) in the community and hospital cohort settings.Subjects and Methods:The study comprised of 200 cases of staphylococcal pyodermas, derived from the community (150 cases) and hospital (50 cases). Patients were evaluated based on their clinical presentation; antibiotic susceptibility was tested using the Kirby-Bauer disk diffusion method.Statistical Analysis Used:Statistical significance between individual attributes between the community and HA staphylococcal pyoderma groups was analyzed using Chi-square test and mean differences using student's t-test.Results:Factors associated with community-associated (CA) pyodermas were young age (P = 0.0021), primary pyodermas, and involvement of extremities, while those with HA pyodermas were middle age, secondary pyodermas, and significantly increased body surface involvement (P = 0.041). Incidence of CA-MRSA was 11.3%, while that of HA-MRSA was 18%.Conclusions:A high level of resistance to first-line drugs such as penicillin, ciprofloxacin and cotrimoxazole was observed, more so in the hospital strain than in the community strain. S. aureus demonstrated good susceptibility to cephalosporins. Though the two strains of MRSA differed clinically, they showed 100% sensitivity to vancomycin and linezolid.

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Bacteriological profile of community-acquired pyodermas with special reference to methicillin resistant Staphylococcus aureus

Cited by 14 publications

References 0 publications

Antimicrobial resistance in India: A review

Antimicrobial resistance in India: A review

Clinical and bacteriological aspects of pyoderma

The clinical spectrum and antibiotic sensitivity patterns of staphylococcal pyodermas in the community and hospital

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