Bacteriocin (monocin) interactions among Listeria monocytogenes strains

Curtis, Gordon D W; Mitchell, R. L.

doi:10.1016/0168-1605(92)90030-7

Cited by 22 publications

(15 citation statements)

References 7 publications

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“…Regarding the strictly genus-specific action of Listeria phages (Loessner & Busse, 1990;Loessner, 1991), transgeneric inhibition is most probably not due to defective phages. This would also explain the contradiction between our finding that only a relatively small fraction of Listeria strains (17 YO) produce true defective phages and reports of other groups, which stated that 58% (Wilhelms & Sandow, 1989), 76% (Ortel, 1978 or 98 Yo (Curtis & Mitchell, 1992) of Listeria strains produce bactericidal substances. Following Bradley & Dewar (1966), and in order to clarify the nomenclature, we suggest that the term 'monocin' should be used only when the bactericidal principle is a defective phage particle, as confirmed by electron microscopy.…”

Section: Discussioncontrasting

confidence: 56%

“…Bactericidal substances are produced by L. monoytogenes (Curtis & Mitchell, 1992;Hamon & PCron, 1963;Mollerach e t al., 1988 ;Ortel, 1978 ;Wilhelms & Sandow, 1989), but were not studied in structural detail. Sword & Pickett (1 961) reported that their Listeria strains produced substances ' possibly analogous to colicins or colicin-like agents '.…”

Section: Discussionmentioning

confidence: 99%

“…Since then, many Listeria strains were reported to produce bactericidal substances, previously designated as mono-On: Fri, 11 May 2018 07:22:27 R. Z I N K , M. J. LOESSNER a n d S. SCHERER cins or listeriocins (Hamon & PCron, 1963;Ortel, 1978;Wilhelms & Sandow, 1989). Curtis & Mitchell (1992) and Mollerach et al (1988) described these substances to be more similar to bacteriocins, but did not perform any electron microscopical examinations. Although monocins are useful in Listeria typing (Ortel, 1978;Curtis & Mitchell, 1992;Zink et al, 1994), none have yet been examined in detail.…”

Section: Introductionmentioning

confidence: 99%

“…Curtis & Mitchell (1992) and Mollerach et al (1988) described these substances to be more similar to bacteriocins, but did not perform any electron microscopical examinations. Although monocins are useful in Listeria typing (Ortel, 1978;Curtis & Mitchell, 1992;Zink et al, 1994), none have yet been examined in detail. First, the aim of the present study was to investigate relationships between monocins and intact Listeria phages using protein data, morphological studies and DNA/DNA hybridization.…”

Section: Introductionmentioning

confidence: 99%

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Charaterization of cryptic prophages (monocins) in Listeria and sequence analysis of a holin/endolysin gene

Zink¹,

Loessner²,

Scherer³

1995

Microbiology

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~Monocins in Listeria were induced by UV-irradiation of liquid cultures, and defective phage particles were purified from the lysates. Electron microscopy showed flexible, non-contractile bacteriophage-tail-like particles, consisting of specific proteins of molecular mass 2 0 4 5 kDa and pl4-6-6.7. These particles were able to lyse listerial cells. DNA sequence homologies between chromosomal DNA of monocin-producing strains and labelled Listeria phage DNAs were inferred from DNNDNA hybridizations, suggesting that most of the prophage DNA is still present in the listerial chromosome. An endolysin gene cpl2438 was cloned from listerial chromosomal DNA and was identified by its expression of lytic activity against Listeria cells in a bioassay. The gene consists of 864 nt encoding a protein of 287 aa with a calculated molecular mass of 32975 Da (CPL2438). This is in good agreement with the size of a protein observed in SDS-PAGE after overexpression of the lytic protein in Escherichia coli. The nucleotide sequence of a putative holin gene (ho12438, 291 nt) upstream of cpl2438 was determined after PCR-amplification of listerial DNA and it shows typical features common to the holin gene family. Expression of the encoded protein (HOU438,95 aa, 101 kDa) in E. coli was found to be lethal for the host cells. The results underline the close relationship between monocins and intact Listeria bacteriophages, indicating that monocins are incompletely assembled phage particles derived from cryptic prophages of Lisferia, probably including the phage lysin. I I

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Section: Discussioncontrasting

confidence: 56%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Charaterization of cryptic prophages (monocins) in Listeria and sequence analysis of a holin/endolysin gene

Zink¹,

Loessner²,

Scherer³

1995

Microbiology

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“…Historically, interest in the inhibitors produced by Listeria spp. was primarily with regard to their usefulness for the development of phage typing schemes for L. monocytogenes (7,19,27,41,45). To date, there are only a few reports documenting the occurrence of isolates which produce bacteriocin-like activities (17,24).…”

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confidence: 99%

Identification of a New Plasmid-Encoded sec -Dependent Bacteriocin Produced by Listeria innocua 743

Kalmokoff¹,

Banerjee²,

Cyr³

et al. 2001

Appl Environ Microbiol

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Listeria innocua 743 produces an inhibitory activity demonstrating broad-spectrum inhibition of Listeria monocytogenes isolates. Gel-electrophoretic analysis of culture supernatants indicated that two inhibitors with different molecular weights were produced by this strain. Insertion of Tn917 into a 2.9 Kb plasmid (pHC743) generated mutants with either an impaired ability or a loss in ability to produce one of the inhibitors. This finding confirms that the phenotype is dependent on the structural and immunity gene only and that export of this bacteriocin is sec dependent. This is the first confirmation of bacteriocin production in a Listeria spp., and it is of interest that this bacteriocin is closely related to the pediocin family of bacteriocins produced by lactic acid bacteria.

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Listeria

McLauchlin¹

2010

Topley &Amp; Wilson's Microbiology and Microbial Infections

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Bacteriocin (monocin) interactions among Listeria monocytogenes strains

Cited by 22 publications

References 7 publications

Charaterization of cryptic prophages (monocins) in Listeria and sequence analysis of a holin/endolysin gene

Charaterization of cryptic prophages (monocins) in Listeria and sequence analysis of a holin/endolysin gene

Identification of a New Plasmid-Encoded sec -Dependent Bacteriocin Produced by Listeria innocua 743

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