Bactericidal activity of various antibiotics versus tetracycline-loaded chitosan microspheres against Pseudomonas aeruginosa biofilms

Melake, Nahla A.; Mahmoud, Hanaa; Al-Semary, Mona T.

doi:10.5897/ajmr12.709

Cited by 3 publications

(2 citation statements)

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“…Sulfadiazine or doxycycline were added to PAB agar in concentrations based on MIC values for P. aeruginosa from the literature as no ECOFF values were available on EUCAST [ 38 ]. Specifically 8 mg/mL doxycycline and 128 mg/L sulfadiazine were added to the PAB agar to select the presumable resistant population [ [39] , [40] , [41] , [42] , [43] , [44] , [45] , [46] , [47] , [48] ]. Lincomycin was not added to PAB agar as most Gram-negative bacteria have a natural resistance against the lincosamides [ 49 ].…”

Section: Methodsmentioning

confidence: 99%

The impact of antibiotic residues on resistance patterns in leek at harvest

Huygens

Rasschaert

Bart

et al. 2023

Heliyon

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Section: Methodsmentioning

confidence: 99%

The impact of antibiotic residues on resistance patterns in leek at harvest

Huygens

Rasschaert

Bart

et al. 2023

Heliyon

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“…The antimicrobial activity of CS and its derivatives, including NPs, is contingent on a complex interplay between intrinsic factors and environmental conditions. 48,53 This multifaceted nature is reected in the variability in reported antimicrobial effects against PA across the existing literature. In our study, we observed a relatively low MIC 50 for TMC-NPs, suggesting their effectiveness against PA.…”

Section: Preparation Of Cs/tmc-nps For Antimicrobial Applicationsmentioning

confidence: 99%

Exploring the antimicrobial potential of chitosan nanoparticles: synthesis, characterization and impact on Pseudomonas aeruginosa virulence factors

Maršík,

Maťátková,

Kolková

et al. 2024

Nanoscale Adv.

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Approaches for Mitigating Microbial Biofilm-Related Drug Resistance: A Focus on Micro- and Nanotechnologies

et al. 2021

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Biofilms play an essential role in chronic and healthcare-associated infections and are more resistant to antimicrobials compared to their planktonic counterparts due to their (1) physiological state, (2) cell density, (3) quorum sensing abilities, (4) presence of extracellular matrix, (5) upregulation of drug efflux pumps, (6) point mutation and overexpression of resistance genes, and (7) presence of persister cells. The genes involved and their implications in antimicrobial resistance are well defined for bacterial biofilms but are understudied in fungal biofilms. Potential therapeutics for biofilm mitigation that have been reported include (1) antimicrobial photodynamic therapy, (2) antimicrobial lock therapy, (3) antimicrobial peptides, (4) electrical methods, and (5) antimicrobial coatings. These approaches exhibit promising characteristics for addressing the impending crisis of antimicrobial resistance (AMR). Recently, advances in the micro- and nanotechnology field have propelled the development of novel biomaterials and approaches to combat biofilms either independently, in combination or as antimicrobial delivery systems. In this review, we will summarize the general principles of clinically important microbial biofilm formation with a focus on fungal biofilms. We will delve into the details of some novel micro- and nanotechnology approaches that have been developed to combat biofilms and the possibility of utilizing them in a clinical setting.

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Bactericidal activity of various antibiotics versus tetracycline-loaded chitosan microspheres against Pseudomonas aeruginosa biofilms

Cited by 3 publications

References 0 publications

The impact of antibiotic residues on resistance patterns in leek at harvest

The impact of antibiotic residues on resistance patterns in leek at harvest

Exploring the antimicrobial potential of chitosan nanoparticles: synthesis, characterization and impact on Pseudomonas aeruginosa virulence factors

Approaches for Mitigating Microbial Biofilm-Related Drug Resistance: A Focus on Micro- and Nanotechnologies

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