Bactericidal activity of tuftsin

Martinez, Jean; Winternitz, F.

doi:10.1007/bf00225303

Cited by 21 publications

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

The Value of Partial Splenic Autotransplantation in Patients With Portal Hypertension

Zhang

Chen²,

Kaiser³

et al. 2002

Arch Surg

View full text Add to dashboard Cite

Setting: University hospital. Patients: Twenty patients (19 men and 1 woman; aged 33-80 years) suffering from portal hypertension and liver cirrhosis were randomly allocated into 2 groups. Each group consisted of 10 patients. Interventions: All patients underwent modified Sugiura operation. In the control group, splenectomy was performed, while partial splenic autotransplantation into the retroperitoneal space was additionally completed in the splenic autotransplantation group. Main Outcome Measures: Serum tuftsin and IgM were measured preoperatively and 2 months after surgery. Dynamic scintigraphy with technetium Tc 99m-labeled heat-damaged erythrocytes was performed at 2-month intervals during the 8-month follow-up. Results: There was no statistical difference in the mortality of the groups. The preoperative levels of serum tuftsin and IgM showed no statistical difference between groups. However, although these measures had decreased remarkably in the control group 2 months after operation (PϽ.001 for serum tuftsin; P =.04 for serum IgM), they remained stable in the splenic autotransplantation group (P =.25 for serum tuftsin; P =.12 for serum IgM). Four patients within the splenic autotransplantation group showed positive scanning of the transplanted splenic fragment during follow-up, whereas there was no positive scanning in the control group. RESULTS MORBIDITY AND MORTALITY An 80-year-old patient from the splenic autotransplantation group, who had had severe chronic obstructive pulmonary disease for more than 30 years, died of

show abstract