Bactericidal action of &lt;i&gt;Alpinia galanga&lt;/i&gt; essential oil on food-borne bacteria

Prakatthagomol, Waranee; Klayraung, Srikanjana; Okonogi, Siriporn

doi:10.5582/ddt.2011.v5.2.84

Cited by 12 publications

(4 citation statements)

References 22 publications

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“…2011 ; Prakatthagomol et al. 2011 ; Sakunpak & Panichayupakaranan 2012 ). Some of these show high ability to inhibit the growth of drug resistant strains such as Punica granatum L. (Lythraceae) (Voravuthikunchai & Kitpipit 2005 ), Quercus infectoria Oliv.…”

Section: Discussionmentioning

confidence: 99%

In vitro antibacterial activity and in vivo therapeutic effect of Sesbania grandiflora in bacterial infected silkworms

Anantaworasakul

Hamamoto

Sekimizu

et al. 2017

Pharmaceutical Biology

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Context: Antibiotic resistance is a serious problem worldwide. Searching for new potential agents is, therefore, essential. The bark of Sesbania grandiflora (L.) Pers. (Fabaceae) has been used in folk medicine against various diseases.Objective: To investigate the antibacterial activity of S. grandiflora bark and explore the therapeutic effect of the highest potent fraction.Materials and methods: Bacteria and healthy silkworms were exposed to three fractionated extracts (3.1–400 mg/mL) of S. grandiflora bark from hexane (HXF), chloroform (CFF), and ethyl acetate (EAF). The sets of bacteria were incubated at 37 °C while silkworms were kept at 27 °C for 24 h. To evaluate the therapeutic effect, silkworms infected with bacteria were exposed to the extracts (0.5–60 mg/mL) and incubated at 27 °C for 52 h. Qualitative analysis of the most potent extract was done using HPLC.Results: EAF showed the highest activity with MIC against methicillin resistant Staphylococcus aureus (MRSA) and vancomycin resistant enterococci (VRE) of 1.6 and 0.4 mg/mL, respectively, and against Gram-negative Escherichia coli and Pseudomonas aeruginosa of 6.2 and 3.1 mg/mL, respectively. It is nontoxic to silkworms with LC50 >400 mg/mL and has high therapeutic effect on infected silkworms with EC50 of 1.9 mg/mL. EAF consists of at least five major compounds, one of them is gallic acid. The activity of EAF is higher than the sum of individual activities of separated compounds.Discussion and conclusion: These results suggest that EAF is a promising antibacterial extract, suitable for further investigation in rodents infected with drug resistant bacteria.

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Section: Discussionmentioning

confidence: 99%

In vitro antibacterial activity and in vivo therapeutic effect of Sesbania grandiflora in bacterial infected silkworms

Anantaworasakul

Hamamoto

Sekimizu

et al. 2017

Pharmaceutical Biology

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“…Therefore, several medicinal plants have been investigated for antibacterial activities in order to be an alternative choice for prevention and treatment of infectious diseases including oral infections (4). Many plant extracts including plant essential oils have been reported to have potential inhibitory effects against many strains of Gram-negative and Gram-positive pathogenic bacteria (5)(6)(7). The in vitro inhibition of some oral bacteria by the extracts of Antrodia camphorate (8) and Prunus mume (9) has been reported.…”

Section: Discussionmentioning

confidence: 99%

Effects of Piper betle fractionated extracts on inhibition of Streptococcus mutans and Streptococcus intermedius

Phumat

Khongkhunthian

Wanachantararak

et al. 2018

DD&T

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The overgrowth of certain strains of normal flora in oral cavity can cause many kinds of oral infections or diseases such as carries, periodontitis, and gingivitis. Prevention and treatment of these diseases are usually achieved by chemical antiseptics. However, these chemicals are found as negative impacts of human health hazards and accession of microbial resistance. The present study explores the potential of Piper betle extracts on inhibition of two oral pathogenic bacteria; Streptococcus mutans DMST 41283 and Streptococcus intermedius DMST 42700. P. betle demonstrated significantly higher inhibitory activity against both pathogenic strains than Acacia catechu, Camellia sinensis, Coccinia grandis, Solanum indicum, and Streblus asper. Among fractionated extracts of P. betle from several solvents, the extract from ethyl acetate (Pb-EtOAc) possessed the widest inhibition zone of 11.0 ± 0.1 and 11.3 ± 0.4 mm against both bacterial strains, respectively. Pb-EtOAc showed the same minimum inhibitory concentration of 0.5 mg/mL against both strains, whereas its minimum bactericidal concentrations were 2.0 and 0.5 mg/mL against S. mutans and S. intermedius, respectively. HPLC analysis demonstrated that the major active compound of Pb-EtOAc was 4-allylpyrocatechol. It was found that the killing kinetics of Pb-EtOAc against both test strains were time and dose dependent. Scanning electron microscopy micrographs showed the morphological changes and depletion of the tested pathogens indicating cell destruction after exposure to Pb-EtOAc. It is confirmed that Pb-EtOAc is potentially effective against both oral pathogens and might be used as natural alternative agents in prevention and treatment of oral infections caused by oral pathogenic bacteria.

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“…Komponen utama lainnya yang menyusun minyak atsiri ini antara lain geranial, camphen, dan arcurcumen (Malek et al,2005). Beberapa penelitian melaporkan bahwa minyak atsiri jahe efektif dalam menghambat mikroba (Natta et al, 2008;Singh et al, 2008;Prakatthagomol et al, 2011). Minyak jahe merah memiliki aroma sangat tajam, sehingga perlu dikombinasikan dengan minyak atsiri yang memiliki aroma harum, salah satunya minyak jeruk manis.…”

Section: Pendahuluanunclassified

Potensi Minyak Jahe Merah Dan Minyak Jeruk Manis Sebagai Bahan Aktif Alami Dalam Pembuatan Handsanitizer

Tandikura¹,

Sipahelut

Augustyn³

2022

EKOLMIPA

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The COVID-19 pandemic that has hit the world requires everyone to maintain hand hygiene as a way to avoid this virus. Hand sanitizer is an instant option for cleaning hands. The use of essential oils in hand sanitizers is considered safer than alcohol. This study aims to study the antiseptic activity, physical and organoleptic characteristics of hand sanitizers in combination with red ginger oil and sweet orange oil. This study was designed using a completely randomized design (CRD) with one factor, namely a combination of red ginger oil and sweet orange oil, with three treatment levels: 75% : 25%, 50% : 50%, dan 25% : 75%. Parameters analyzed included antisepticby Replika method, dispersibility, pH, density, homogeneity and organoleptic tests (texture, aroma, and color). The results showed that hand sanitizer with a combination treatment of 25% red ginger oil and 75% sweet orange oil had a stronger antiseptic effectiveness compared to other treatments. 6.2 cm which shows the consistency of the hand sanitizer that is comfortable when used, the hand sanitizer gel is homogeneous, without any coarse grains and is still organoleptically acceptable for texture, aroma and color.

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Bactericidal action of <i>Alpinia galanga</i> essential oil on food-borne bacteria

Cited by 12 publications

References 22 publications

In vitro antibacterial activity and in vivo therapeutic effect of Sesbania grandiflora in bacterial infected silkworms

In vitro antibacterial activity and in vivo therapeutic effect of Sesbania grandiflora in bacterial infected silkworms

Effects of <i>Piper betle</i> fractionated extracts on inhibition of <i>Streptococcus mutans</i> and <i>Streptococcus intermedius </i>

Potensi Minyak Jahe Merah Dan Minyak Jeruk Manis Sebagai Bahan Aktif Alami Dalam Pembuatan Handsanitizer

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