Bactericidal Action and Industrial Dye Degradation of Graphene Oxide and Polyacrylic Acid-Doped SnO₂Quantum Dots:In SilicoMolecular Docking Study

Abstract

The present work demonstrates the systematic incorporation of different concentrations of graphene oxide (GO) into a fixed amount of polyacrylic acid (PAA)-doped SnO 2 quantum dots (QDs) through a coprecipitation approach. The research aimed to evaluate the catalytic and antibacterial actions of GO/PAA-SnO 2 QDs. Moreover, optical properties, surface morphologies, crystal structures, elemental compositions, and d-spacings of prepared QDs were examined. X-ray diffraction patterns revealed the tetragonal configuration of SnO 2 , and the crystallinity of QDs was suppressed upon dopants verified by the SAED patterns. Electronic spectra identified the blue shift by incorporating GO and PAA led to a reduction in band gap energy. Fourier transform infrared spectra showed the existence of rotational and vibrational modes associated with the functional groups during the synthesis process. A drastic increase in the catalytic efficacy of QDs was observed in the neutral medium by including dopants, indicating that GO/PAA-SnO 2 is a promising catalyst. GO/PAA-SnO 2 showed strong bactericidal efficacy against Escherichia coli (E. coli) at higher GO concentrations. Molecular docking studies predicted the given nanocomposites, i.e., SnO 2 , PAA-SnO 2 , and GO/PAA-SnO 2 , as potential inhibitors of beta-lactamase E. coli and DNA gyrase E. coli .

Catalytic green synthesis of Tin(IV) oxide nanoparticles for phenolic compounds removal and molecular docking with EGFR tyrosine kinase

“…The negative and low docking score value indicate that the compounds underwent strong and favorable binding interactions. Our findings are compatible with those found in the literature 43 , and RMSD refine 1.1985 Å is less than 2 Å, i.e., a good result, as depicted in Fig. 14 .…”

Investigation of Structural and Antibacterial Properties of WS2-Doped ZnO Nanoparticles

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