Bacterial Vaginosis and Behavioral Factors Associated With Incident Pelvic Inflammatory Disease in the Longitudinal Study of Vaginal Flora

Turpin, Rodman; Tuddenham, Susan; He, Xin; Klebanoff, Mark A.; Ghanem, Khalil G.; Brotman, Rebecca M.

doi:10.1093/infdis/jiab103

Cited by 16 publications

(8 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Amerika Birleşik Devletlerinde 2956 kadınla yapılan bir çalışma vajinal duşu PİH ile ilişkilendirmiştir. 16 Kanadalı 1435 kadınla yapılan kesitsel bir çalışmada önceki altı ayda vajinal duş alan katılımcıların bakteriyel vajinozis bildirme ihtimalinin 7 kat daha fazla olduğu belirtilmiştir. 17 Nepalli 160 hamile olmayan kadın üzerinde yapılan çalışmada, günlük vajinal duş alışkanlığı olan kadınların bakteriyel vajinozise yakalanma olasılığının ara sıra duş yapan kadınlara göre daha yüksek olduğu gösterilmiştir.…”

Section: Vajinal Duşunclassified

Pelvik inflamatuar hastalık risk faktörleri ve korunma yöntemleri

Taş,

Gençtürk

2024

SYBD

View full text Add to dashboard Cite

Pelvik inflamatuar hastalık, endojen servikovajinal mikroorganizmaların serviksten uterusa doğru ilerlemesi sonucu enfeksiyonun, üst genital sisteme yayılması ile ortaya çıkmaktadır. Pelvik inflamatuar hastalık vakalarının çoğunluğu cinsel yolla bulaşan bir enfeksiyonla ilişkilidir. Chlamydia Trachomatis ve Neisseria Gonorrhoeae cinsel yolla bulaşan enfeksiyonlar içerisinde pelvik inflamatuar hastalığa neden olan en yaygın patojenlerdir. Pelvik inflamatuar hastalık bakteriyel vajinoz gibi cinsel yolla bulaşmayan enfeksiyonlardan da kaynaklanabilir. En sık 15 ila 25 yaş arası kadınlarda görülmektedir. Hastalığın belirti ve bulguları hafif seyredebilir veya asemptomatik olabilir. Bu nedenle de geç tespit edilebilmektedir. Zamanında tespit edilemediğinde gelişen başlıca sorunlar kronik pelvik ağrı, infertilite ve ektopik gebeliktir. Bu nedenle pelvik inflamatuar hastalık tanısına katkıda bulunabilecek risk faktörlerini bilmek tanının daha erken konulmasına yardımcı olabilir. Güncel literatür doğrultusunda hazırlanan bu derlemenin amacı pelvik inflamatuar hastalık risk faktörlerini bilerek bu hastalıktan korunmanın sağlanmasıdır.

show abstract

Section: Vajinal Duşunclassified

Pelvik inflamatuar hastalık risk faktörleri ve korunma yöntemleri

Taş,

Gençtürk

2024

SYBD

View full text Add to dashboard Cite

show abstract

“…Additionally, many people douche because of symptoms of BV, thus associations between douching and lower counts of lactobacilli may not be causally related. However, because of the possible association with decreased vaginal lactobacilli, and its association with pelvic inflammatory disease, douching should be discouraged ( 141 ).…”

Section: Complementary and Alternative Optionsmentioning

confidence: 99%

Bacterial vaginosis: a review of approaches to treatment and prevention

Abbe

Mitchell

2023

Front. Reprod. Health

View full text Add to dashboard Cite

Bacterial vaginosis (BV) is a common cause of vaginitis worldwide and is associated with serious reproductive health outcomes, including increased risk of preterm birth, sexually transmitted infections, and pelvic inflammatory disease. The current and only FDA-approved treatment regimens for BV are antibiotics, such as metronidazole and clindamycin. Antibiotics provide a short-term cure for bacterial vaginosis; however, fail to provide a consistent long-term cure for many women. Fifty to eighty percent of women experience a BV recurrence within a year of completing antibiotic treatment. This may be because after antibiotic treatment, beneficial strains of Lactobacillus, such as L. crispatus, do not recolonize the vagina. In the absence of an effective long-term cure, patients, providers, and researchers are exploring different approaches to treatment and prevention, resulting in a rapid evolution of perspectives on BV pathogenesis and approaches to management. Current areas of investigation for BV management include probiotics, vaginal microbiome transplantation, pH modulation, and biofilm disruption. Behavioral modifications that may help include smoking cessation, condom use and hormonal contraception. Additional strategies considered by many people include dietary modification, non-medical vaginally applied products, choice of lubricant, and treatments from medical practices outside of allopathic medicine. This review aims to provide a comprehensive and up to date outline of the landscape of ongoing and potential treatment and prevention strategies for BV.

show abstract

“…BV is clinically relevant as it affects millions of women annually and is associated with multiple complications [ 8 , 9 ] including pelvic inflammatory disease [ 10 ], preterm delivery [ 11 ], miscarriage [ 12 ], infertility [ 13 ], and an increased risk of acquisition of sexually transmitted infections (STIs) including HIV [ 14 ], gonorrhea, and chlamydia [ 15 ]. Furthermore, despite initial response to antimicrobial therapy, a large proportion of women with BV experience multiple episodes of recurrent disease [ 16 ].…”

Section: Introductionmentioning

confidence: 99%

An Indirect Fluorescence Microscopy Method to Assess Vaginal Lactobacillus Concentrations

Lima,

Muzny,

Cerca

2024

Microorganisms

View full text Add to dashboard Cite

Lactobacillus species are the main colonizers of the vaginal microbiota in healthy women. Their absolute quantification by culture-based methods is limited due to their fastidious growth. Flow cytometry can quantify the bacterial concentration of these bacteria but requires the acquisition of expensive equipment. More affordable non-culturable methods, such as fluorescence microscopy, are hampered by the small size of the bacteria. Herein, we developed an indirect fluorescence microscopy method to determine vaginal lactobacilli concentration by determining the correlation between surface area bacterial measurement and initial concentration of an easily cultivable bacterium (Escherichia coli) and applying it to lactobacilli fluorescence microscopy counts. In addition, vaginal lactobacilli were quantified by colony-forming units and flow cytometry in order to compare these results with the indirect method results. The colony-forming-unit values were lower than the results obtained from the other two techniques, while flow cytometry and fluorescence microscopy results agreed. Thus, our developed method was able to accurately quantify vaginal lactobacilli.

show abstract

Bacterial Vaginosis and Behavioral Factors Associated With Incident Pelvic Inflammatory Disease in the Longitudinal Study of Vaginal Flora

Cited by 16 publications

References 49 publications

Pelvik inflamatuar hastalık risk faktörleri ve korunma yöntemleri

Pelvik inflamatuar hastalık risk faktörleri ve korunma yöntemleri

Bacterial vaginosis: a review of approaches to treatment and prevention

An Indirect Fluorescence Microscopy Method to Assess Vaginal Lactobacillus Concentrations

Contact Info

Product

Resources

About