Bacterial Toxins

Bernard, Marina de; Montecucco, Cesare

doi:10.1002/9783527692156.ch4

Cited by 2 publications

(2 citation statements)

References 110 publications

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“…It is known that antibiotic resistance in biofilms and at the cellular level is ensured by different mechanisms. However, despite the differences, these processes are largely synergistic: traditional resistance mechanisms of planktonic cells can also act in biofilms, and biofilms enhance resistance at the cellular level [31][32][33]. The study results were also confirmed in the works of Zakirov I. I. et al and Carcione D. et al [33,34].…”

Section: Discussionsupporting

confidence: 75%

The Effect of Cell-Free Nontuberculous Mycobacterium Supernatants on Antibiotic Resistance and Biofilm Formation of Opportunistic Pathogens

Shchuplova,

Gogoleva

2023

Bacteria

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The presence of nontuberculous mycobacteria in biofilms on the surface of medical devices may affect the opportunistic pathogens that are common inhabitants of such biofilms. This study assessed the effect of Mycolicibacterium iranicum cell-free supernatants on biofilm formation and antibiotic susceptibility of Escherichia coli and Staphylococcus epidermidis differing in the anti-hemoglobin activity level. The cell-free supernatants have been shown to stimulate biofilm formation and also help reduce susceptibility of opportunistic pathogens to a number of antibiotics.

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Section: Discussionsupporting

confidence: 75%

The Effect of Cell-Free Nontuberculous Mycobacterium Supernatants on Antibiotic Resistance and Biofilm Formation of Opportunistic Pathogens

Shchuplova,

Gogoleva

2023

Bacteria

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“…3,4 The complex extracellular polymer networks provide protection against various environmental stresses and biological and chemical agents. 3,5 Biofilm formation can be influenced by the hydrodynamics and surface properties of the surrounding environment. 6 Biofilms are beneficial in the natural environment to promote microbe survival and symbiosis 7 as well as in synthetic systems for applications in agriculture, 8 food fermentation, 8 bioremediation 3,9 and corrosion inhibition.…”

Section: Introductionmentioning

confidence: 99%

Slippery lubricant-infused silica nanoparticulate film processing for anti-biofouling applications

Li Sip,

Jacobs,

Morales

et al. 2023

Journal of Applied Biomaterials & Functional Materials

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Microbial biofilm build-up in water distribution systems can pose a risk to human health and pipe material integrity. The impact is more devastating in space stations and to astronauts due to the isolation from necessary replacement parts and medical resources. As a result, there is a need for coatings to be implemented onto the inner region of the pipe to minimize the adherence and growth of biofilms. Lubricant-infused surfaces has been one such interesting material for anti-biofouling applications in which their slippery property promotes repellence to many liquids and thus prevents bacterial adherence. Textured and porous films are suitable substrate candidates to infuse and contain the lubricant. However, there is little investigation in utilizing a nanoparticulate thin film as the substrate material for lubricant infusion. A nanoparticulate film has high porosity within the structure which can promote greater lubricant infusion and retention. The implementation as a thin film structure aids to reduce material consumption and cost. In our study, we utilized a well-studied nanoporous thin film fabricated via layer-by-layer assembly of polycations and colloid silica and then calcination for greater stability. The film was further functionalized to promote fluorinated groups and improve affinity with a fluorinated lubricant. The pristine nanoporous film was characterized to determine its morphology, thickness, wettability, and porosity. The lubricant-infused film was then tested for its lubricant layer stability upon various washing conditions and its performance against bacterial biofilm adherence as a result of its slippery property. Overall, the modified silica nanoparticulate thin film demonstrated potential as a base substrate for lubricant-infused surface fabrication that repelled against ambient aqueous solvents and as an anti-biofouling coating that demonstrated low biofilm coverage and colony forming unit values. Further optimization to improve lubricant retention or incorporation of a secondary function can aid in developing better coatings for biofilm mitigation.

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Bacterial Toxins

Cited by 2 publications

References 110 publications

The Effect of Cell-Free Nontuberculous Mycobacterium Supernatants on Antibiotic Resistance and Biofilm Formation of Opportunistic Pathogens

The Effect of Cell-Free Nontuberculous Mycobacterium Supernatants on Antibiotic Resistance and Biofilm Formation of Opportunistic Pathogens

Slippery lubricant-infused silica nanoparticulate film processing for anti-biofouling applications

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