Bacterial Succinoglycans: Structure, Physical Properties, and Applications

Abstract

Succinoglycan is a type of bacterial anionic exopolysaccharide produced from Rhizobium, Agrobacterium, and other soil bacteria. The exact structure of succinoglycan depends in part on the type of bacterial strain, and the final production yield also depends on the medium composition, culture conditions, and genotype of each strain. Various bacterial polysaccharides, such as cellulose, xanthan, gellan, and pullulan, that can be mass-produced for biotechnology are being actively studied. However, in the case of succinoglycan, a bacterial polysaccharide, relatively few reports on production strains or chemical and structural characteristics have been published. Physical properties of succinoglycan, a non-Newtonian and shear thinning fluid, have been reported according to the ratio of substituents (pyruvyl, succinyl, acetyl group), molecular weight (Mw), and measurement conditions (concentration, temperature, pH, metal ion, etc.). Due to its unique rheological properties, succinoglycan has been mainly used as a thickener and emulsifier in the cosmetic and food industries. However, in recent reports, succinoglycan and its derivatives have been used as functional biomaterials, e.g., in stimuli-responsive drug delivery systems, therapeutics, and cell culture scaffolds. This suggests a new and expanded application of succinoglycan as promising biomaterials in biomedical fields, such as tissue engineering, regenerative medicine, and pharmaceuticals using drug delivery.

Production and Characterization of a Novel Exopolysaccharide from Ramlibacter tataouinensis

“…It is therefore responsible for cell defense mechanisms in general and in particular, in the context of the semi-arid conditions in which this bacterial strain was isolated, this EPS allows it to adapt to desiccation. Its structure is unique and completely different from that of other bacterial cysts such as Azotobacter , which is an alginate [ 44 ], and also different from the well-known succinoglycan, xanthan, gellan, pullulan, hyaluronan, and cellulose produced by soil bacterial species [ 45 ]. Some details remain to be confirmed with 1D 13 C NMR, NOESY, and HMBC NMR spectra that would identify the sequence and assembly of the identified units in the spectrum.…”

Biopolymer from Water Kefir as a Potential Clean-Label Ingredient for Health Applications: Evaluation of New Properties

“…In general, the endothermic peak is related to the breaking of hydrogen bonds and the loss of hydroxyl groups when the material is warmed. Consequently, the formation of the endothermic peak is because of the disruption of the structure [86].…”

Avaliação Do Potencial De Migração De Aditivos Adicionados Em Filmes Comerciais De PVC

“…A atividade viscosificante, a qual consiste na alta viscosidade em soluções aquosas, é uma das principais características do succinoglucana. A viscosidade elevada é devido, principalmente, à presença de cerca de 10% de ácido succínico (Halder et al, 2017;Jeong, Kim, Hu, & Jung, 2022).…”

“…Pequenas concentrações de succinoglucana produzem grandes aumentos na estabilidade. Em algumas situações, em que proteínas estão envolvidas no sistema emulsificante, verificou que a adição de Ca 2+ na presença de succinoglucana melhorou a estabilidade da emulsão, diminuindo a separação de fases (Halder et al, 2017;Jeong et al, 2022).…”