Bacterial Profile of Middle Ear Infections, Coeixstence of Pseudomonas, Proteus Species in Middle Ear Infections and Their Antibiotic Sensitivity Pattern

Abstract

Introduction: Otitis media is the leading cause of hearing impairment in developed countries. The permanent hearing loss due to otitis media has the prevalence of 2 to 35 per 10,000. The major pathogens of acute otitis media are i. e; S. pneumonia, S.pyogenes, Moraxella catarrhalis, Haemophilus influenza and rarely S.aureus and those of chronic otitis media are i. e; Pseudomonas, Proteus, E. coli and S. aureus.
 Objective: To determine the bacterial profile of otitis media, to estimate the coexistence of pseudomonas and proteus and to check the antibiotic sensitivity pattern of different bacteria in otitis media.
 Material and methods: Sample size of 85 samples is estimated by using 95% confidence level, 10% absolute precision with expected percentage of susceptibility pattern of otopathogens as 32.8% the research article” Microbiological profile and their antimicrobial sensitivity pattern in patients of otitis media with ear discharge” (15). Samples from outdoor patients of ENT department , Mayo Hospital, Lahore, with discharging ear of all ages and both genders were taken excluding patients with external ear infections.
 Study design: Cross sectional study.
 Setting: Department of Diagnostic Microbiology, the Mayo Hospital and the Institute of King Edward Medical University, Lahore
 Sample technique: Non Probability Purposive Sampling
 Results: Out of total 85 samples, 38(44.7%) and 47(55.3%) were male and female respectively. Mean age + SD was 24 + 16 years. Out of 85 samples 58 (68.2%) cases were positive with 27 (46.5%) samples positive in males and 31 (53.4%) samples positive in females. Out of positive cases, 18(31.0%) were Gram positive and 30(51.7%) cases showed growth of Gram negative organisms. The coexistence of Pseudomonas and Proteus was found in 12(20.6%) of positive cases.