Bacterial profile, antibiotic susceptibility pattern and associated factors among pregnant women with Urinary Tract Infection in Goba and Sinana Woredas, Bale Zone, Southeast Ethiopia

Abstract

ObjectiveUrinary tract infection (UTI) is one of the commonest infections affecting millions worldwide, especially pregnant women. It can lead to poor maternal and perinatal outcomes. Untreated UTI can be associated with serious obstetric complications. So the objective of present study was to determine the bacterial profile, antibiotic susceptibility pattern and associated factors of UTI among pregnant women in Goba and Sinana Woredas, Bale Zone, Southeast Ethiopia.ResultsThe overall prevalence of UTI was 44/169 (26%) with 18/51 (35.3%) in symptomatic and 26/118 (22%) in asymptomatic pregnant women, respectively. Of the 44 bacterial isolates, E. coli 12/44 (27.3%), K. pneumonia 9/44 (20.5%) and S. marcescens 4/44 (9.1%) were the commonest bacterial pathogens. C. freundii 3/44 (6.8%), M. morganii 3/44 (6.8%), P. aeruginosa 3/44 (6.8%) and S. enteritidis 3/44 (6.8%) isolates were the moderately identified bacterial species. K. oxytoca 1/44 (2.3%) was the least common bacterium to be detected. The antibiotic susceptibility pattern showed that 90.9%, 88.6% and 86.3% of the isolates were sensitive to amoxicillin/clavulanic acid, gentamycin and norfloxacin, respectively. Significant bacteriuria was associated with low educational status (p = 0.024; AOR = 6.617; CI = 1.87–9.94) and kidney problems (p = 0.018; AOR = 0.286; CI = 1.19–2.81).Electronic supplementary materialThe online version of this article (10.1186/s13104-018-3910-8) contains supplementary material, which is available to authorized users.

<p>Prevalence of Asymptomatic Bacteriuria, Associated Factors and Antimicrobial Susceptibility Profile of Bacteria Among Pregnant Women Attending Saint Paul’s Hospital Millennium Medical College, Addis Ababa, Ethiopia</p>

“…This finding is comparable with a study conducted in Dessie, Ethiopia, 5 Hawassa, Ethiopia, 6 and Bale, Ethiopia. 36 However, most Gram-negative bacteria were resistant to amoxicillin (79.3%), amoxicillin-clavulanic acid (37.9%).…”

Aetiological Profile and Antibiogram of Urinary Isolates Causing UTI in Patients Attending a Tertiary Care Hospital of Western Odisha

“…In our study out of 730 samples, 238 (33%) showed significant bacteriuria which was higher than Afroza et al (6.87%) 10 , Arshi et al (30%), 11 Angamiet et al (28.1%) 12 but lower than Nzalie et al (58.8%), 13 Maheswary et al (63.51%), 15 Prakash et al (53.82%), 16 Taye et al (36%), 16 khan et al (54.4%), 17 Manjunath et al (42.37%) 18 it was very similar to Dash et al (34.5%) 19 most probably due to similar environmental niche. BYC was positive in 2 % growth and it was lower than Manjunath et al (4.5%) 18 and Venkatesh et al (6%).…”

“…The least common bacteria was Citrobacter (1%).This finding was very similar with Dash et al 19 (68.8% E. coli followed by 9.7% Enterococci), Manjunath et al (60.7% E. coli followed by 12.1% Enterococci species) 18 and Arshi et al(56.7% E. coli followed by 13.1% Enterococci species) 11 but not consistent with the most of the studies worldwide. Klebsiella was the 2 nd most common bacteria in Nzalie et al 13 Angamiet et al, 12 Prakash et al, 15 Taye et al, 16 Jubina et al 21 , khan et al, 17 Mahajan et al 28 Akochere ET al 29 showed that Klebsiella was the least prevalent (1.2%) bacteria in UTI. Ehinmidu ET al 30 showed that Pseudomonas was the most common (32%) bacteria in UTI.…”

Prevalence and associated risk factors of urinary tract infection in pregnancy at the Douala General Hospital, Cameroon: a case–control study

“…Several microorganisms have been associated with UTI although Escherichia coli is the most frequent accounting for 80 % to 90 % of UTI's in pregnancy [1,[9][10][11].…”

“…044 AP/MINSANTE/HGD/DM/03/19). We respected the ethical principles of the Helsinki declaration while carrying out this study [10] and reporting was according to the Strobe guidelines for a case-control study.…”