Bacterial profile and antimicrobial susceptibility patterns of otitis media among children in Qatar

Abstract

Background: Otitis Media (OM) common diseases affecting children below 5 years of age with a harmful effect on their hearing and health status. Data about the bacterial profile and current antimicrobial resistance status of Otitis Media in the region is scarce. Objective of this study determine the causative organisms of Otitis Media and antimicrobial susceptibility patterns among children in a Primary Health Care Corporation (PPHC) centers, Qatar.Methods: A cross-sectional study was conducted in PPHC from Jan 2016 to Dec 2017. A total of 181 patients with Otitis Media presented to PHCC centers were enrolled in the study. Socio-demographic and clinical data were documented and analysed.Results: A total of 181 children, an almost equal number of male (49.7%) and female (50.3%) participants were involved in the study. 51.4% of participants were ≤5 years of age. Bacteria isolated were: Pseudomonas Aeruginosa (27.6%), Hemophilus Influenza (13.3%), Staphylococcus Aureus (11.6%), Methicillin-Resistant Staphylococcus Aureus (MSRA) (11.0%), Streptococcus Pyogenes (10.5%), Streptococcus Pneumonia (6.6%), Moraxella Catarrhalis (2.2%), Klebsiella Pneumonia (0.6%). The sensitivity of Pseudomonas Aeruginosa was (100%) to cotrimoxazole, vancomycin, and piperacillin, (96%) to cefepime and gentamicin, and was (88.2%) to ciprofloxacin. MRSA sensitivity was (100%) to vancomycin, rifampicin, and teicoplanin, (89%) to clindamycin.Conclusion: Pseudomonas Aeruginosa was the most frequent isolated bacteria. An overall antimicrobial resistance pattern seen in bacteria isolates ranges from 0% to 66.7%. The antimicrobial-resistant rate was observed for Ampicillin, Augmentin, and cefuroxime whereas ciprofloxacin, cefepime, chloramphenicol, cotrimoxazole, gentamicin, vancomycin, and amikacin were found effective for the isolated resistant bacteria.

Antibiotic resistance pattern of Streptococcus pneumoniae among infants younger than six months of age with acute otitis media in Erbil city

“…This is in agreement with earlier study conducted by Waheeb; et al, reported that S. pneumoniae was the predominant agent [45]. In contrast other studies show Staphylococcus aureus [46], Pseudomonas aeruginosa [47], and Haemophilus influenzae [48]. Variation in the frequency rates of these pathogens possibly related to the different laboratory procedures used to identify bacteria, aerobic or anaerobic conditions, season, age group, vaccination status against different pathogenic bacteria and different health care programs in various geographical locations.…”

Detection of FOX-AmpC-β-lactamase gene and antibiogram of AmpC-beta-lactamase-producing pathogens isolated from chronic suppurative otitis media patients in Nigeria

“…Chronic suppurative otitis media (CSOM) is a chronic inflammation of the middle ear and the mastoid cavity with perforated tympanic membrane, resulting in ear discharges persisting for at least 14 days ( 1 , 2 ). If not properly treated, the disease might have long-term effects on language development, early communication, educational process, physiological and cognitive development, and auditory processing ( 3 ). By one year of age, at least 60% of children have experienced an episode, and 17% have suffered at least 3 episodes of acute otitis media (AOM) ( 4 ) which may progress to CSOM.…”