Pharmaceutical Sciences Encyclopedia 2010
DOI: 10.1002/9780470571224.pse072
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Bacterial Mutation Assay

Abstract: The bacterial mutation assay is a reliable and extensively used short‐term assay for initial screening of chemicals/drugs for their potential mutagenic/carcinogenic activity. But short‐term tests have their own advantages and limitations. This article presents an overview of the utilization of bacterial systems for mutagenic and carcinogenic chemicals.

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