Bacterial leakage of mineral trioxide aggregate as compared with zinc-free amalgam, intermediate restorative material, and super-EBA as a root-end filling material

Fischer, Edward J.; Arens, Donald E.; Miller, Chris H.

doi:10.1016/s0099-2399(98)80178-7

Cited by 146 publications

(108 citation statements)

References 7 publications

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“…The joints are sealed with sticky wax and the tooth is covered with layers of nail polish 9 . This model had been followed by others to test root end filling materials 10,11,8 . In a similar model used by Bal et al 12 , the tooth roots are sealed in the lumen of a latex tubing segment with cyanoacrylate and inserted down into culture medium.…”

Section: Discussionmentioning

confidence: 99%

“…The limitations of the in vitro microleakage studies and the quest for obtaining clinically relevant data, prompted the researchers to develop bacterial leakage models [8][9][10][11][12][13][14][15] . The basic idea here is to allow bacteria to migrate through the repair material and measure the penetration time using microbiological techniques with repaired teeth, simulating conditions as close as possible to the clinical conditions.…”

mentioning

confidence: 99%

“…Though a considerable number of bacterial leakage studies has been performed in the past few years, no acceptable or standardized model did evolve [8][9][10][11][12][13][14][15] . Custom-made set-ups are used, the simplest being enclosing the tooth in a plastic tube and inserting into a bigger tube with culture medium, after sealing the boundaries.…”

mentioning

confidence: 99%

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An In Vitro Model for Evaluating Bacterial Leakage Through Endodontic Repair Materials

2013

IOSR-JDMS

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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An In Vitro Model for Evaluating Bacterial Leakage Through Endodontic Repair Materials

2013

IOSR-JDMS

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“…22 Not listed by Hargreaves et al, but another consistent observation of these reports, is the use of MTA to complete the coronal seal which has known biological conductive properties to ensure an adequate coronal seal. 23 While these case reports have been labelled as either pulpal revascularization and ⁄ or regenerative endodontics with continued root development and apical closure, it is unknown what tissue has indeed been regenerated. Some authors have suggested that there may be remaining viable pulpal tissue in necrotic teeth that initiates the regenerative process.…”

Section: Discussionmentioning

confidence: 99%

Regenerative endodontics – biologically‐based treatment for immature permanent teeth: a case report and review of the literature

Thomson

Kahler

2010

Australian Dental Journal

114

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Background: A paradigm shift in the treatment of immature, necrotic teeth has occurred with biologically-based principles and regenerative endodontic protocols replacing traditional 'apexification' procedures. Preliminary research suggests that stem and progenitor cells from the pulp and ⁄ or periodontium contribute to continued root development when regenerative procedures are followed. Methods: A mandibular premolar tooth with a chronic periapical abscess was irrigated with sodium hypochlorite with minimal instrumentation and then dressed with tri-antibiotic paste consisting of ciprofloxacin, metronidazole and amoxicillin. At a subsequent visit a blood clot was evoked in the canal by irritating periapical tissues and the canal sealed with mineral trioxide aggregate, glass ionomer cement and composite resin. Results: Resolution of apical periodontitis and the draining sinus, continued root maturation and apical closure occurred over an 18-month period. The tooth became responsive to pulp sensibility testing. Conclusions: It is important that dentists recognize the potential of regenerative endodontics in the treatment of necrotic, immature teeth. Initial management should involve irrigation with sodium hypochlorite only. Intra-canal medicaments, such as calcium hydroxide, are contraindicated as they inhibit further root growth. This report uses a variation of the triantibiotic paste currently recommended for regenerative procedures that avoided the discolouration of the crown associated with current protocols. Regenerative endodontics with continued root growth may reduce the risk of fracture and premature tooth loss associated with traditional 'apexification' procedures where the root remains thin and weak.

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“…In microleakage studies carried out in vitro it has been shown to be superior to IRM, SuperEBA and amalgam. [30][31][32][33] It is a very biocompatible material and histological assessment carried out on Cynomolgus monkeys following periradicular surgery and root-end filling with MTA has showed no signs of periradicular inflammation. 34 MTA has been shown to stimulate cytokine release 35 and the production of interleukins 36 which suggests that it is a bioactive material capable of promoting hard tissue formation, unlike other existing root-end filling materials.…”

Section: Apexificationmentioning

confidence: 99%

Weakened anterior roots – intraradicular rehabilitation

2005

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This paper highlights the fact that many anterior teeth requiring restoration are severely weakened having wide, flared canal spaces, and thin dentinal walls that are prone to fracture. Traditionally these teeth have been restored using metal posts and are often unsuccessful because of lack of retention or root fracture. This paper describes how mineral trioxide aggregate (MTA) can be used to form an immediate apical seal rather than waiting months for apexification. Weakened roots can be reinforced using dentine bonding agents and composite resin and if insufficient coronal tooth structure is present a quartzfibre post can be placed to retain a composite core.  Root filled teeth are often compromised by incomplete root formation, secondary caries around posts, inappropriate post space preparation, and internal resorption.  Traditional methods of restoration using metal posts and pins are often unsatisfactory.  Instead of waiting for the formation of a calcific bridge during apexification, mineral trioxide aggregate can be placed as an immediate apical seal.  Weakened roots can be reinforced using dentine bonding agents, composite resin and quartzfibre posts.

show abstract

Bacterial leakage of mineral trioxide aggregate as compared with zinc-free amalgam, intermediate restorative material, and super-EBA as a root-end filling material

Cited by 146 publications

References 7 publications

An In Vitro Model for Evaluating Bacterial Leakage Through Endodontic Repair Materials

An In Vitro Model for Evaluating Bacterial Leakage Through Endodontic Repair Materials

Regenerative endodontics – biologically‐based treatment for immature permanent teeth: a case report and review of the literature

Weakened anterior roots – intraradicular rehabilitation

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