Bacterial keratitis treated by strengthened antibiotic eye drops: An 18 months review of clinical cases and antibiotic susceptibilities

Saillard, Justine; Spiesser-Robelet, Laurence; Gohier, Philippe; Briot, Thomas

doi:10.1016/j.pharma.2017.11.005

Cited by 13 publications

(11 citation statements)

References 19 publications

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“…aureus isolates generally are susceptible to vancomycin. 163,164 (See Appendix 6 for instructions for preparing fortified topical antibiotics.) A case series of vancomycin-resistant enterococcus demonstrated that topical linezolid can be used, 156 with no ocular surface toxicity.…”

Section: Treatment Initial Treatmentmentioning

confidence: 99%

Bacterial Keratitis Preferred Practice Pattern®

et al. 2019

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Section: Treatment Initial Treatmentmentioning

confidence: 99%

Bacterial Keratitis Preferred Practice Pattern®

et al. 2019

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“…Sustained release iodine is effective with low toxicity, but has a high incidence of sensitivity reactions. It has been shown to be effective against some biofilms 46–48 . Hypochlorous acid combines efficacy with relatively low cytotoxicity.…”

Section: Infection Controlmentioning

confidence: 99%

“…Treatment should be limited to 2 weeks due to concerns about inducing antibiotic resistance 38,49 . Several antibiotics are approved for topical treatment of ocular and periocular wounds and for treatment of external otitis 48,49 . Over‐the‐counter antibiotic ointments like bacitracin and Neosporin may be useful short‐term adjuncts, but up to 2% of adults now have hypersensitivity reactions to bacitracin due to injudicious and prolonged exposures 38 …”

Section: Infection Controlmentioning

confidence: 99%

“…It has been shown to be effective against some biofilms. [46][47][48] Hypochlorous acid combines efficacy with relatively low cytotoxicity.…”

Section: Treatmentmentioning

confidence: 99%

“…After debridement the wound is treated with an antimicrobial such as hypochlorous acid, cadexomer iodine, Ag+ and others. Washing and scrubbing the wound will also decrease biofilm presence 47,48 …”

Section: Infection Controlmentioning

confidence: 99%

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Chronic wounds: Treatment consensus

Eriksson

Liu

Schultz

et al. 2022

Wound Repair Regeneration

139

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The Wound Healing Foundation (WHF) recognised a need for an unbiased consensus on the best treatment of chronic wounds. A panel of 13 experts were invited to a virtual meeting which took place on 27 March 2021. The proceedings were organised in the sub‐sections diagnosis, debridement, infection control, dressings, grafting, pain management, oxygen treatment, outcomes and future needs. Eighty percent or better concurrence among the panellists was considered a consensus. A large number of critical questions were discussed and agreed upon. Important takeaways included that wound care needs to be simplified to a point that it can be delivered by the patient or the patient's family. Another one was that telemonitoring, which has proved very useful during the COVID‐19 pandemic, can help reduce the frequency of interventions by a visiting nurse or a wound care center. Defining patient expectations is critical to designing a successful treatment. Patient outcomes might include wound specific outcomes such as time to heal, wound size reduction, as well as improvement in quality of life. For those patients with expectations of healing, an aggressive approach to achieve that goal is recommended. When healing is not an expectation, such as in patients receiving palliative wound care, outcomes might include pain reduction, exudate management, odour management and/or other quality of life benefits to wound care.

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