Bacterial Interactions with Dental and Medical Materials

Melo, Mary Anne S.

doi:10.3390/jfb11040083

Cited by 6 publications

(3 citation statements)

References 16 publications

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“…In general, macroroughness is described to improve bone–implant interactions, but it is well known that the optimal surface roughness should be about 1 µm to promote the osteogenic differentiation of MSCs [ 39 , 40 ]. Unfortunately, increasing surface roughness can promote the microbial colonization of the implant surface, as initial bacterial adhesion begins at sites that offer shelter [ 41 , 42 ]. Several studies have shown that, in order to reduce bacterial adhesion, a nanoscale surface with a roughness of <200 nm is the most effective, since the depth and period of the nanostructures are smaller than most bacteria [ 12 , 42 , 43 ].…”

Section: Discussionmentioning

confidence: 99%

Polarization of Femtosecond Laser for Titanium Alloy Nanopatterning Influences Osteoblastic Differentiation

Maalouf

Khalil

Maïo³

et al. 2022

Nanomaterials

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Ultrashort pulse lasers have significant advantages over conventional continuous wave and long pulse lasers for the texturing of metallic surfaces, especially for nanoscale surface structure patterning. Furthermore, ultrafast laser beam polarization allows for the precise control of the spatial alignment of nanotextures imprinted on titanium-based implant surfaces. In this article, we report the biological effect of beam polarization on human mesenchymal stem cell differentiation. We created, on polished titanium-6aluminum-4vanadium (Ti-6Al-4V) plates, a laser-induced periodic surface structure (LIPSS) using linear or azimuthal polarization of infrared beams to generate linear or radial LIPSS, respectively. The main difference between the two surfaces was the microstructural anisotropy of the linear LIPSS and the isotropy of the radial LIPSS. At 7 d post seeding, cells on the radial LIPSS surface showed the highest extracellular fibronectin production. At 14 days, qRT-PCR showed on the same surface an increase in osteogenesis-related genes, such as alkaline phosphatase and osterix. At 21 d, mineralization clusters indicative of final osteoinduction were more abundant on the radial LIPSS. Taken together, we identified that creating more isotropic than linear surfaces enhances cell differentiation, resulting in an improved osseointegration. Thus, the fine tuning of ultrashort pulse lasers may be a promising new route for the functionalization of medical implants.

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Section: Discussionmentioning

confidence: 99%

Polarization of Femtosecond Laser for Titanium Alloy Nanopatterning Influences Osteoblastic Differentiation

Maalouf

Khalil

Maïo³

et al. 2022

Nanomaterials

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“…The last decade brought significant improvements of mechanical material properties as well as surface characteristics and biocompatibility of composites used in dentistry [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 ]. Focus on new bioactive compounds in composites to prevent dental caries development and progression has led researchers to the use of nanotechnologies [ 9 , 10 ]. Composite configuration has significant impact not only on 3D-printed appliance properties [ 11 , 12 , 13 ] but also on adhesion efficacy when used as adhesive for an appliance [ 14 , 15 ].…”

Section: Introductionmentioning

confidence: 99%

Utilization of a 3D Printed Orthodontic Distalizer for Tooth-Borne Hybrid Treatment in Class II Unilateral Malocclusions

et al. 2022

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This paper introduces a novel method of 3D designing and 3D printing of a hybrid orthodontic tooth-borne personalized distalizer for treatment of unilateral Class II malocclusion. Research objectives were to clinically utilize 3D printed distalizers, appraise feasibility of this technique and compare two different biocompatible photopolymers (white and transparent). Frequency of distalizers’ debonding and patients’ aesthetical perception was evaluated on the set of 12 complete orthodontic treatments. The mean duration of treatment period with a bonded distalizer was 6.4 months. All cases were adults with unilateral Class II malocclusion managed with a hybrid approach as a part of Invisalign® comprehensive treatment. Results showed that such perspective practice is feasible for 3D design and in-office 3D printing of a personalized distalizer. Results also showed no clinically significant differences between both studied biopolymers. The paper discusses an evaluation of such personalized distalizer functionality with regard to the current state of the art and compares to conventional prefabricated alternatives like a Carriere® Distalizer™ appliance. Research showed a preference of patients towards transparent biocompatible photopolymer instead of the white A2 shade. The paper concludes that additive manufacturing from dental resins is a viable method in personalization and in-office 3D printing of orthodontic auxiliaries, particularly distalizers. New materials for orthodontic 3D printing endow enhanced individualization, thus more efficient treatment.

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“…Research led to significant improvements of mechanical strength, surface characteristics and biocompatibility of composites used in dentistry [1 -8]. Focus on new bioactive compounds in composites to prevent dental caries development and progression has led researchers to use of nanotechnologies [9,10]. Composite configuration has significant impact not only on 3D-printed appliance properties [11 -13] but also on adhesion efficacy when used as adhesive for an appliance [14,15].…”

Section: Introductionmentioning

confidence: 99%

3D Printed Orthodontic Distalizer with Individual Base for Tooth-Borne Hybrid Approach in Class II Unilateral Malocclusions Treatment

Thurzo¹,

Urbanová²,

Novák³

et al. 2021

Preprint

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Aim of this research paper is to introduce a novel method of hybrid orthodontic tooth-borne distalizer treatment of class II malocclusion by using 3D printed biocompatible personalized distalizer. Explains 3D designing, printing and clinical application of individualized biocompatible medical device dedicated for orthodontic teeth distalization. Compares such distalizer manufactured from two different biocompatible photopolymers (white and transparent). Evaluates their clinical performance and also patients’ aesthetical perception. Clinical part includes comparison of treatment debonding on the set of 12 complete orthodontic treatments with uni-lateral class II malocclusion managed with hybrid approach (CAT-Invisalign with 3D printed distalizer). Paper offers an evaluation of the personalized distalizer functioning in regard to current publications and comparison to conventional prefabricated alternatives like Carriere® Distalizer™ appliance. Results showed no significance of material differences on clinical performance of such individualized distalizers. Research showed preference of patients towards transparent biocompatible photopolymer instead of white A2 shade.

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Bacterial Interactions with Dental and Medical Materials

Abstract: Fundamental scientific understanding of oral diseases associated with tissue-contacting dental and medical devices is primordial to facilitate pathways for their translation to clinical use [...]

Cited by 6 publications

References 16 publications

Polarization of Femtosecond Laser for Titanium Alloy Nanopatterning Influences Osteoblastic Differentiation

Polarization of Femtosecond Laser for Titanium Alloy Nanopatterning Influences Osteoblastic Differentiation

Utilization of a 3D Printed Orthodontic Distalizer for Tooth-Borne Hybrid Treatment in Class II Unilateral Malocclusions

3D Printed Orthodontic Distalizer with Individual Base for Tooth-Borne Hybrid Approach in Class II Unilateral Malocclusions Treatment

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