Bacterial Endocarditis due to Haemophilus Parainfluenzae

Blair, Donald C.; Walker, William J.; Sodeman, Thomas; Pagano, Terry

doi:10.1378/chest.71.2.146

Cited by 24 publications

(6 citation statements)

References 6 publications

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“…5 There is an inverse correlation between vegetation mass and favourable clinical response. 6 Our patient probably experienced subclinical cerebral embolisation before presentation to hospital. It is widely believed that an embolic event is unlikely after 2 weeks of appropriate antibiotic therapy.…”

Section: Discussionmentioning

confidence: 78%

A case of Haemophilus Parainfluenzae endocarditis during pregnancy

et al. 2008

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Section: Discussionmentioning

confidence: 78%

A case of Haemophilus Parainfluenzae endocarditis during pregnancy

et al. 2008

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“…Although H parainfluenzae endocarditis is quite uncommon, review of the literature suggests that those who are infected by this particular type of endocarditis may share similar characteristics. [1][2][3][4][5][6][7] Patients with endocarditis due to H parainfluenzae, and other HACEK organisms, tend to be of younger age, [1][2][3][4] and a large majority of patients suffer from embolic phenomena, such as stroke. 1,[5][6][7] In addition, if antibiotic therapy is delayed, the potential for valvular damage is significant.…”

Section: Discussionmentioning

confidence: 99%

“…Review of the literature demonstrates that previously reported cases of H parainfluenzae endocarditis have also been associated with severe systemic complications, including septic cerebral emboli and mitral valve perforation. [1][2][3][4][5][6][7]…”

Section: Introductionmentioning

confidence: 99%

Haemophilus parainfluenzae Endocarditis Associated With Maxillary Sinusitis and Complicated by Cerebral Emboli in a Young Man

Duzenli

Dwyer

Carey

2017

Journal of Investigative Medicine High Impact Case Reports

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HACEK endocarditis is often difficult to diagnose given the slow-growing characteristics of the organisms involved. Haemophilus parainfluenzae, one of the HACEK organisms, is an uncommon cause of endocarditis. We describe a case of a previously healthy young man with H parainfluenzae endocarditis that was associated with maxillary sinusitis and severe systemic complications, including septic cerebral emboli and mitral valve perforation. Previously reported cases have also described a predilection for younger people, cardiac valve pathology, and a high prevalence of stroke.

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“…As in our patient, the mitral valve is a common site of infection, and vegetations tend to be large, again as in our patient. Early reports suggested an adverse correlation between vegetation size and outcome [7]. The size of the vegetations is further responsible for the tendency for occlusive disease associated with H. parainfluenzae endocarditis [8].…”

Section: Discussionmentioning

confidence: 99%

Acute Haemophilus parainfluenzae endocarditis: a case report

et al. 2009

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IntroductionNumerous pathogens can cause infective endocarditis, including Haemophilus parainfluenzae. H. parainfluenzae is part of the H. aphrophilus, Actinobacillus actinomycetemcomitans, Cardiobacterium hominis, Eikenella corrodens, and Kingella kingae group that may cause about 3% of the total endocarditis cases, and is characterized by a subacute course and large vegetations.Case presentationAcute H. parainfluenzae endocarditis developed in a 54-year-old woman, with no underlying predisposing factors. The patient presented with fever of 3 days duration and a severe headache. Magnetic resonance imaging of the brain revealed multiple cerebral emboli with hemorrhagic foci. Upon suspicion of endocarditis, cardiac transesophageal ultrasonography was performed and revealed massive vegetations. The patient underwent emergency mitral valve replacement, and was further treated with ceftriaxone. Blood cultures grew H. parainfluenzae only after valve replacement, and a 6-week course of ceftriaxone was prescribed.ConclusionWe underline the typical presentation of large vegetations in H. parainfluenzae endocarditis, which are associated with embolic phenomena and resulting severity. Although the majority of the few cases reported in the literature are subacute in progress, our case further underlines the possibility that H. parainfluenzae endocarditis may develop rapidly. Thus, awareness of the imaging characteristics of the pathogen may enhance early appropriate diagnosis and therapeutic response.

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Bacterial Endocarditis due to Haemophilus Parainfluenzae

Cited by 24 publications

References 6 publications

A case of Haemophilus Parainfluenzae endocarditis during pregnancy

A case of Haemophilus Parainfluenzae endocarditis during pregnancy

Haemophilus parainfluenzae Endocarditis Associated With Maxillary Sinusitis and Complicated by Cerebral Emboli in a Young Man

Acute Haemophilus parainfluenzae endocarditis: a case report

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