Bacterial Colonization and Home Mechanical Ventilation: Prevalence and Risk Factors

González-Moro, José Miguel Rodríguez; Vivero, G. Andrade; Díez, Javier de Miguel; Martín, Soledad López; Sánchez, C.; Alonso, José L.; Ramos, Pilar

doi:10.1016/s1579-2129(06)60341-8

Cited by 15 publications

(13 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Chronic respiratory insufficiency in patients with NMD is treated with NIV . The equipment for NIV, for example, the ventilator itself, attached humidifiers or voice prosthesis are frequently colonized with potential pathogenic bacteria or C. albicans . In patient with CF, care contamination of the respiratory equipment is a frequent problem .…”

Section: Discussionmentioning

confidence: 99%

Upper airway microbial colonization in patients with neuromuscular disorders

et al. 2016

View full text Add to dashboard Cite

Background and objective: Inherited neuromuscular disorders (NMD) inevitably result in severe lung volume restriction and cough insufficiency associated with high morbidity and mortality. The aim of this retrospective study was to evaluate whether the airways of patients with NMD are colonized with potential pathogenic microorganisms that might contribute to the pulmonary morbidity in NMD. Methods: In this cross-sectional study, cough swabs were obtained and cultured for microbiological analyses from 77 patients with NMD and different degrees of lung volume restriction and cough insufficiency. Upper airway microbial colonization was compared to lung function parameters and cough peak flow values. Results: Upper airway microbial colonization with potential pathogenic pathogens was identified in 39/77 (51%) of the subjects. Upper airway microbial colonization was associated with lower forced vital capacity (% pred.) 26.6 ± 19.7 versus 41.8 ± 20.4, P < 0.001 and cough peak flow (l/min) 125 ± 55 versus 207 ± 100, P < 0.001. In the subgroup colonized with potential pathogenic Gram-negative bacteria or Staphylococcus aureus forced vital capacity and cough peak flow remained significantly lower compared with subjects without upper airway colonization (FVC (% pred.): 22.6 ± 16.5 vs 37.9 ± 21.5, P = 0.003; CPF (l/min): 123 ± 60 vs 179 ± 93, P = 0.013). Conclusion: Severe respiratory compromise in patients with NMD is associated with upper airway microbial airway colonization, which might contribute to respiratory morbidity/insufficiency.

show abstract

Section: Discussionmentioning

confidence: 99%

Upper airway microbial colonization in patients with neuromuscular disorders

et al. 2016

View full text Add to dashboard Cite

show abstract

“…Rodrigues et al conducted a consecutive series on 40 patients using NIV for various indications including restrictive lung disease. 3 Fifty-three percent of patients cleaned their NIV mask and tubing infrequently (monthly, sporadically, or never) and 67.5% were visually dirty. Fifteen percent of the NIV equipment were contaminated and 25% of patients were colonized by potentially pathogenic microorganisms (PPM), most commonly Staphylococcus aureus.…”

Section: Patient-to-device Transmission or Body Site To Respiratory T...mentioning

confidence: 96%

“…The authors did not provide a protocol for adequate maintenance of devices. 3 Another study of bacterial contamination of NIV equipment included 23 patients with restrictive lung disease using NIV. 4 Two equipment cleaning regimens were compared.…”

Section: Patient-to-device Transmission or Body Site To Respiratory T...mentioning

confidence: 99%

See 1 more Smart Citation

Persistent Pseudomonas aeruginosa infection associated with non-invasive ventilation in a child with spinal muscular atrophy type 1

Chacko

Sly

Kidd

et al. 2021

Journal of Clinical Sleep Medicine

View full text Add to dashboard Cite

Current standards of care suggest the use of non-invasive positive pressure ventilation (NIV) in children with spinal muscular atrophy and symptomatic respiratory failure. Theoretical concerns exist regarding NIV equipment as a source of infection in restrictive lung disease due to the possibility of prolonged NIV device use, greater risk in acquiring infections, and difficulties in managing and clearing infections. NIV devices may draw pathogens through the air inlet port that may contaminate the internal surfaces. These pathogens may then infect children with spinal muscular atrophy. We present a case of 2 genetically identical Pseudomonas aeruginosa cultures from both the patient's NIV device and from nasopharyngeal samples. This infection persisted both in nasopharyngeal aspirate cultures and from NIV equipment cultures despite the use of an eradication program involving both the child and the NIV device.

show abstract

“…One study surveyed 40 patients and found that more than 50% of them did not clean their home NIV equipment at weekly intervals, as recommended by most manufacturers, whereas 15% of the participants did not clean their equipment at all. 7 The authors stated that their survey asked about the cleaning methods patients used, but these data were not reported or analyzed in the published paper. Similarly, Busa et al 12 surveyed 12 pediatric patients regarding their adherence to the recommended cleaning protocol for NIV nasal masks and found that steps in their recommendations were often missed.…”

Section: Introduction and Purposementioning

confidence: 99%

Survey of Home Cleaning Practices With Noninvasive Ventilation Equipment

Milross

McGuiness

et al. 2022

Cardiopulm Phys Ther J

View full text Add to dashboard Cite

Home noninvasive ventilation (NIV) equipment is often observed to be dirty, potentially increasing patients' risk of respiratory infection. This study aimed to describe the cleaning practices of home NIV patients. Methods: This single-site, cross-sectional, observational study surveyed 100 patients from the respiratory failure clinic regarding cleaning instructions, cleaning habits, barriers, and motivators to cleaning. Open-ended responses were analyzed with basic content analysis and closed categorical responses with frequencies and percentages. Results: Of 100 participants, 77% responded. Cleaning instructions most commonly recalled included cleaning with soapy water for masks (26/47, 55%), head straps (19/47, 40%), and tubing (21/47, 45%); vinegar solution for humidifiers (9/39, 23%); and replacing filters (14/39, 36%). Fourteen respondents reported barriers to cleaning, including forgetfulness (7/14, 50%) and physical difficulties (6/14, 43%). Commonly reported cleaning practices included soapy water to soak masks (28/77, 36%) and tubing (35/77, 46%), weekly masks (34/77, 44%) and tubing cleaning (29/77, 38%), vinegar solution to clean humidifiers for the 36 humidifier users (15/36, 44%), monthly humidifier cleaning (13/36, 36%), and monthly filter cleaning/replacement (36/77, 47%). Conclusion: Few respondents could recall specific instructions about when and how to clean their equipment. Many reported routine cleaning, with varied methods and frequencies. Our results will inform future NIV equipment cleaning educational package design.

show abstract

Bacterial Colonization and Home Mechanical Ventilation: Prevalence and Risk Factors

Cited by 15 publications

References 12 publications

Upper airway microbial colonization in patients with neuromuscular disorders

Upper airway microbial colonization in patients with neuromuscular disorders

Persistent Pseudomonas aeruginosa infection associated with non-invasive ventilation in a child with spinal muscular atrophy type 1

Survey of Home Cleaning Practices With Noninvasive Ventilation Equipment

Contact Info

Product

Resources

About