Bacterial Cellulose Towards Functional Medical Materials

Biocompatible Bacterial Cellulose-Poly(2-hydroxyethyl methacrylate) Nanocomposite Films

“…Bacterial cellulose (BC) is a unique form of cellulose, produced by several bacteria of the Gluconacetobacter and Sarcina genus, among others [8, 9]. Because of its inherent biocompatibility and unique properties, that arise from the tridimensional network of nano- and microfibrils, bacterial cellulose is becoming a promising biopolymer for several biomedical [6, 10–16] (e.g., wound dressing, artificial skin, and scaffolds for tissue engineering and soft tissue replacement) and technological [17–21] applications (e.g., optical transparent nanocomposites, electronic paper, and fuel cell membranes). BC/polymer nanocomposites have been prepared by simple blending of BC nanofibrils with several polymeric matrices [22–27] or by in situ polymerization of monomers within the cellulose network [16, 28–32].…”

TEMPO-mediated oxidation of bacterial cellulose in a bromide-free system

“…One concern raised in the past with BC is that its superficial neutral charge limited its application in drug application. However, BC was lately tested like artificial contact lens with ofloxacin to treat keratitis [11]. Most recently, several generations of bioreactors have been designed and constructed to grow BC tubes for blood vessel replacement [12,13].…”

Special Nanoskin-ACT-Biological Membranes from Deep Wounds

“…. The structural features of microbial cellulose, its properties and compatibility as a biomaterial for regenerative medicine can be changed by modifying its culture medium [11] or surface modification by physical [12] [13]; chemical methods [14] and genetic modifications [15] to obtain a biomaterial with less rejection when in contact to the body…”