2024
DOI: 10.1039/d3lp00184a
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Bacterial cellulose nanoparticles as a sustainable drug delivery platform for protein-based therapeutics

Gabrielle N. Balistreri,
Ian R. Campbell,
Xinqi Li
et al.

Abstract: Sustainable nanomedicine is an emerging field aiming to address the challenges of scalability, reproducibility, thermal stability, and excessive waste generation for nanotherapeutic manufacturing. Bacterial cellulose (BC) fibers have the potential...

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Cited by 4 publications
(3 citation statements)
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“…2b) indicated the presence of abundant oxygen and nitrogen-containing functional groups on the surface of the GQD-based nanoparticles. These functional groups included –COOH (CO stretch around 1760–1690 cm −1 , C–O stretch around 1320–1210 cm −1 ), –OH (O–H stretch around 3300–2500 cm −1 , O–H bend from 1440–1395 and 950–910 cm −1 ), and –NH 2 (N–H stretch around 3400–3250 cm −1 , N–H bend around 1650–1580 cm −1 , C–N stretch (aromatic amines) around 1335–1250 cm −1 , N–H wag from 910–665 cm −1 ) groups, 74,75 These functional groups contribute to the colloidal stability of FeN/GQDs. Peaks around 680, 520, and 440 cm −1 corresponding to Fe–O bonds were barely detected, indicating a limited content of oxidized iron in the sample.…”
Section: Resultsmentioning
confidence: 99%
“…2b) indicated the presence of abundant oxygen and nitrogen-containing functional groups on the surface of the GQD-based nanoparticles. These functional groups included –COOH (CO stretch around 1760–1690 cm −1 , C–O stretch around 1320–1210 cm −1 ), –OH (O–H stretch around 3300–2500 cm −1 , O–H bend from 1440–1395 and 950–910 cm −1 ), and –NH 2 (N–H stretch around 3400–3250 cm −1 , N–H bend around 1650–1580 cm −1 , C–N stretch (aromatic amines) around 1335–1250 cm −1 , N–H wag from 910–665 cm −1 ) groups, 74,75 These functional groups contribute to the colloidal stability of FeN/GQDs. Peaks around 680, 520, and 440 cm −1 corresponding to Fe–O bonds were barely detected, indicating a limited content of oxidized iron in the sample.…”
Section: Resultsmentioning
confidence: 99%
“…As depicted in Figure 7, the FTIR spectrum of the pure BC film reveals several distinctive peaks indicative of its molecular structure. A notable peak at 2894 cm −1 corresponds to the CH stretching vibrations at the C-6 position, suggesting the presence of alkane or alkene functional groups within the cellulose structure [21]. The spectrum also shows a range of peaks between 1427 and 1315 cm −1 , which represent various functional groups and vibrations inherent to BC.…”
Section: Fourier Transform Infrared Spectroscopy (Ftir)mentioning
confidence: 97%
“…BC's versatility allows for easy tailoring into different formats, such as films, particles, hydrogels, and fibers, making it highly suitable for integration into various wound dressings [21][22][23]. Its properties can also be tailored to address specific needs for various types of wounds.…”
Section: Introductionmentioning
confidence: 99%