Bacterial cellulose matrix with in situ impregnation of silver nanoparticles via catecholic redox chemistry for third degree burn wound healing

An Updated Review on Silver Nanoparticles in Biomedicine

“…The nanocomposites facilitated necrotic tissue clearance, promoted collagen deposition and epidermis neoformation. The scaffolds also determined increased/decreased levels of anti-inflammatory/pro-inflammatory interleukins, respectively, and upregulation of growth factor genes involved in wound healing [411]. Highly antimicrobial electrospun PLA scaffolds modified with nanosilver and cellulose nanofibrils promoted the proliferation and normal growth of ocular epithelial cells, with no proinflammatory reaction.…”

Gamma Ray-Induced Synthesis of Silver Nanoparticles using Bacterial Cellulose as a Multi-Functional Agent and its Application

“…BC has very high purity so that making other puri cation processes (such as deligni cation), which is very energy-consuming for plant cellulose, is unnecessary (Santoso et al, 2020). BC production gained more attention over the last several decades and its potential uses cover very varied elds including food (Padrao et al, 2016;Azeredo et al, 2019) and medical application (Moniri et al, 2017;Pal et al, 2017 andJiji et al, 2020). The ability to use BC in diverse application resulting from its stunning properties that include high purity, biodegradability, three-dimensional (3-D) nano ber, high water holding capacity, good mechanical properties, high crystallinity, and biocompatibility (Shi et al, 2014;Shabanpour et al, 2018;Wang et al, 2019), besides, the availability of incorporating nanostructured materials into BC 3-D network structure make it attractive and appropriate for more application (Torres et al, 2019).…”

“…Nanostructured materials and their applications represent an active area at the scienti c and traditional levels (Xue et al, 2019). Nanoparticles and nanostructured materials have found their way into different elds such as food (Enescu et al, 2019), medicine (Jiji, 2020), environment (Umar et al, 2016), and so on. It is well known that silver nanoparticle materials have been proven to be the most useful because they showed great antimicrobial performance against a wide range of microorganisms including various bacteria and fungi (Siddiqi et al, 2018 andWang et al, 2018).…”

“…Listeria monocytogenes, Proteus mirabilis, and E. coli were resistant to ceftazidime. BC/AgNP composite and streptomycin showed antibacterial potencyMandal et al, 2016; El-Sherbinyet al, 2020, Jiji et al, 2020. the antibacterial activity of AgNPs depends on many factors including size, charge, the concentration of AgNPs(Van Phu et al, 2014, Jiji et al, 2020, and also the stabilizer used (Phu et al, 2014).…”

“…BC/AgNP composite and streptomycin showed antibacterial potencyMandal et al, 2016; El-Sherbinyet al, 2020, Jiji et al, 2020. the antibacterial activity of AgNPs depends on many factors including size, charge, the concentration of AgNPs(Van Phu et al, 2014, Jiji et al, 2020, and also the stabilizer used (Phu et al, 2014). Various mechanisms have been proposed for the antibacterial action of AgNPs, the most common one can be that free silver ions uptake may preventing DNA replication or may cause direct damage to the bacterial cell wall by forming pits in the cell wall that lead to an increase in permeability of cell wall and nal cell death(Jones and Hoek, 2010;Bapat et al, 2018).…”