Bacterial and fungal composition profiling of microbial based cleaning products

Subasinghe, R.M.; Samarajeewa, A.D.; Meier, Matthew J.; Coleman, Gordon; Clouthier, H.; Crosthwait, Jennifer; Tayabali, Azam F.; Scroggins, Richard P.; Shwed, Philip S.; Beaudette, Lee A.

doi:10.1016/j.fct.2017.12.006

Cited by 6 publications

(1 citation statement)

References 33 publications

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“…Voluntary ecolabelling has become increasingly popular [108], yet certification is limited to verifying human safety, product efficacy and environmental preferability; thus, precise identification and concentration of the microbial consortium is not necessary for the certification. The taxonomic genera tend to be the only information provided on product labels, as manufacturers consider the precise identity and composition as proprietary and confidential [109,110].…”

Section: Discussionmentioning

confidence: 99%

Probiotic-Based Sanitation in the Built Environment—An Alternative to Chemical Disinfectants

Ramos

Frantz

2023

Applied Microbiology

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The use of conventional chemical disinfectants is a common practice in built environments and has drastically increased in response to the COVID-19 pandemic. While effective for instantaneous disinfection, the application of chemical disinfectants to indoor surfaces is associated with recontamination and is prone to select for antimicrobial-resistant pathogens. In contrast, probiotic-based sanitation (PBS) relies on the premise that probiotic bacteria, namely apathogenic Bacillus spp., when combined with eco-friendly detergents and applied to indoor surfaces can outcompete and exclude pathogens. Recent in situ studies assessing PBS in healthcare settings have demonstrated overwhelmingly positive results, including significant reductions in pathogen burden, antimicrobial-resistant genes and nosocomial infections, yet these studies are limited in duration and scope. Here, we review results of Bacillus-based PBS in practice, identify knowledge gaps and discuss the considerations for the widespread use of PBS in built environments. In a time when indoor cleaning and disinfection has come to the forefront, PBS may offer an attractive, effective and sustainable alternative to conventional chemical disinfectants.

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Section: Discussionmentioning

confidence: 99%

Probiotic-Based Sanitation in the Built Environment—An Alternative to Chemical Disinfectants

Ramos

Frantz

2023

Applied Microbiology

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Acellular filtrate of a microbial-based cleaning product potentiates house dust mite allergic lung inflammation

Tayabali

Zhang

Fine

et al. 2018

Food and Chemical Toxicology

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Microbial-based cleaning products (MBCPs) contain bacteria and chemical constituents. They are used in consumer applications such as odor reduction, unclogging drains, and surface cleaning. To determine the capacity of a model MBCP to contribute to acute allergic lung inflammation, a two-week repeated exposure regimen was used. Mice were exposed by endotracheal instillation to saline alone, MBCP alone, house dust mites (HDM) alone, or sequentially (i.e., MBCP followed by HDM, HDM followed by MBCP, or HDM + MBCP followed by HDM). Both whole MBCP and acellular MBCP filtrate were investigated, and showed minimal differences in the endpoints examined. HDM exposure caused pulmonary perivascular inflammation, bronchiolar mucous cell metaplasia, elevated bronchoalveolar lavage fluid (BALF) eosinophils, and HDM-specific IgG1. For MBCP, notable changes were associated with sequential exposures. MBCP/HDM caused elevated T2 cytokines in BALF, and elevated neutrophils, eosinophils and IL-5 in peripheral blood. Co-administration of MBCP and HDM followed by HDM resulted in elevated blood and BALF eosinophils and HDM-specific IgE and IgG1. These results demonstrated that acellular MBCP filtrate, and not bacteria within MBCPs, potentiated the acute allergic inflammation to HDM. This methodology could be extended to investigate chronic allergic inflammation and inflammatory potential of other MBCPs and biotechnology products with complex compositions.

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Introduction: Current trends in research and regulation of microbial-based cleaning products

Tayabali

Ashby

2018

Food and Chemical Toxicology

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Bacterial and fungal composition profiling of microbial based cleaning products

Cited by 6 publications

References 33 publications

Probiotic-Based Sanitation in the Built Environment—An Alternative to Chemical Disinfectants

Probiotic-Based Sanitation in the Built Environment—An Alternative to Chemical Disinfectants

Acellular filtrate of a microbial-based cleaning product potentiates house dust mite allergic lung inflammation

Introduction: Current trends in research and regulation of microbial-based cleaning products

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