Bacteria in Midguts of Field-Collected &lt;I&gt;Anopheles albimanus&lt;/I&gt; Block &lt;I&gt;Plasmodium vivax&lt;/I&gt; Sporogonic Development

González-Cerón, Lilia; Santillán, Frida; Rodrı́guez, Mario H.; Mendez, Domingo; Hernández-Ávila, Juan Eugenio

doi:10.1603/0022-2585-40.3.371

Cited by 221 publications

(214 citation statements)

References 11 publications

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“…Similar to the gut microbiota of mammals, the microbiota associated with arthropods plays an important role in host development, pathogen resistance, nutrition, and physiology (69). Microbial symbionts can reduce vector competence, and specific gut microbiota play a protective role in Anopheles mosquitoes against Plasmodium colonization (70)(71)(72)(73). Although knowledge about the function of microbiota in diverse arthropods is still limited, cross-talk between the arthropod, its gut microbiota, and incoming pathogens is likely to be important (9)(10)(11)69).…”

Section: Discussionmentioning

confidence: 99%

Pathogen-mediated manipulation of arthropod microbiota to promote infection

Abraham

Liu

Jutras

et al. 2017

Proc. Natl. Acad. Sci. U.S.A.

219

295

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Arthropods transmit diverse infectious agents; however, the ways microbes influence their vector to enhance colonization are poorly understood.Ixodes scapularisticks harbor numerous human pathogens, includingAnaplasma phagocytophilum,the agent of human granulocytic anaplasmosis. We now demonstrate thatA. phagocytophilummodifies theI. scapularismicrobiota to more efficiently infect the tick.A. phagocytophiluminduces ticks to expressIxodes scapularisantifreeze glycoprotein (iafgp), which encodes a protein with several properties, including the ability to alter bacterial biofilm formation. IAFGP thereby perturbs the tick gut microbiota, which influences the integrity of the peritrophic matrix and gut barrier—critical obstacles forAnaplasmacolonization. Mechanistically, IAFGP binds the terminald-alanine residue of the pentapeptide chain of bacterial peptidoglycan, resulting in altered permeability and the capacity of bacteria to form biofilms. These data elucidate the molecular mechanisms by which a human pathogen appropriates an arthropod antibacterial protein to alter the gut microbiota and more effectively colonize the vector.

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Section: Discussionmentioning

confidence: 99%

Pathogen-mediated manipulation of arthropod microbiota to promote infection

Abraham

Liu

Jutras

et al. 2017

Proc. Natl. Acad. Sci. U.S.A.

219

295

View full text Add to dashboard Cite

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“…Others are stable residents or transients and are lost during digestion or insect moulting (Endris et al 1982, Gonzalez-Ceron et al 2003. The origin and ecological association of the midgut bacteria and the insect host is diffi cult to defi ne.…”

Section: Discussionmentioning

confidence: 99%

Study on the bacterial midgut microbiota associated to different Brazilian populations of Lutzomyia longipalpis (Lutz & Neiva) (Diptera: Psychodidae)

Gouveia¹,

Asensi²,

Zahner³

et al. 2008

Neotrop. entomol.

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“…Iverson et al (1984) reported the presence of Serratia liquefaciens and S. marcescens in all sugar beet root maggot (Diptera: Oititidae) developmental stages, suggesting a symbiosis and a nutritional interdependence between these bacteria and the insect. Gonzalez-Ceron et al (2003) studied the microorganisms present in the midguts of An. albimanus and identified several Serratia and Enterobacter species including S. marcescens, E. cloacae, and E. amnigenus.…”

Section: Discussionmentioning

confidence: 99%

“…Some works have already reported the isolation of microorganisms from the midgut of Culex quinquefasciatus, Anopheles dirus, Anopheles albimanus, and Ae. aegypti , Khampang et al 1999, Luxananil et al 2001, Pidiyar et al 2002, Gonzalez-Ceron et al 2003. The microbiota of Anopheles gambiae and Anopheles funestus was also investigated by 16S rDNA sequence by Lindh et al (2005).…”

Section: We Show For the First Time That The Ventral Diverticulum Of mentioning

confidence: 99%

First isolation of microorganisms from the gut diverticulum of Aedes aegypti (Diptera: Culicidae): new perspectives for an insect-bacteria association

Gusmão

Santos

Marini

et al. 2007

Mem. Inst. Oswaldo Cruz

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We show for the first time that the ventral diverticulum of the mosquito gut (impermeable sugar storage organ) harbors microorganisms. The gut diverticulum from newly emerged and non-fedAedes aegypti (Diptera: Culicidae, Aedini) is the main urban vector for the human diseases yellow fever and dengue fever (Nasci & Miller 1996). The vector control, mainly by insecticide application and elimination of oviposition sites, has been used as the best solution to decrease the diseases incidence. Explore new strategies for blocking the insect transmitted diseases such as dengue fever is urgent in Tropical countries (Sperança & Capurro 2007). Microorganisms associated with the insect may have an important role for human infectious diseases epidemiology. Once a key role bacterium is discovered, it may be modified in order to affect the pathogen development and, consequently, the disease transmission (Azambuja et al. 2005, Riehle & Jacobs-Lorena 2005.The alimentary canal of the mosquito is composed by the foregut, midgut and hindgut. The foregut is involved primarily with ingestion, conduction and storage of food (Romoser 1996). In the alimentary canal of the mosquito three diverticula arise near the posterior end of the esophagus: two from the dorso-lateral and one from the ventral wall of the gut, all surrounded by a thin impermeable cuticle. The ventral diverticulum (VD), or crop, is large and may extend into the abdomen (Dapples & Lea 1974). Usually all three diverticula are filled with air bubbles and are used as food reservoirs (Thompson 1905, Consoli & Lourenço-de-Oliveira 1994. The sugar meal, such as floral nectar, is stored in the diverticula and passes slowly to the midgut, where it is digested (Thompson 1905).Microorganisms play important and often essential roles in the growth and development of many insect species. Despite the importance of these microbial associations with insects there are relatively few studies that elucidate their components and their roles in the interactions. Insects that rely on nutritionally poor diets tend to possess bacterial endosymbionts. Aphids, for example, which subsist solely on plant sap, harbor Buchnera spp., believed to provide amino acids and vitamins to their hosts (Douglas 1989). Blood is known to be severely deficient in essential B vitamins and some amino acids. Bloodsucking arthropods such as ticks, lice, bedbugs, reduviid bugs, and tsetse flies usually harbor symbiotic microorganisms (Buchner 1965). Symbiotic relationships have already been reported for blood feeding insects and some are very well established, as in the case of Rhodnius prolixus that maintains an association with the actinomycete bacteria Rhodococcus rhodnii (Dasch et al. 1984); and tsetse flies genus Glossina, which harbor three distinct symbiotic microorganisms: Wigglesworthia glossinidia, Sodalis glossinidius (commensal), and the parasitic microbe Wolbachia pipientis (Aksoy et al. 1997, Chen et al. 1999.Many key questions about bacteria within the mosquito's midgut remain largely unanswered, and ob...

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Bacteria in Midguts of Field-Collected <I>Anopheles albimanus</I> Block <I>Plasmodium vivax</I> Sporogonic Development

Cited by 221 publications

References 11 publications

Pathogen-mediated manipulation of arthropod microbiota to promote infection

Pathogen-mediated manipulation of arthropod microbiota to promote infection

Study on the bacterial midgut microbiota associated to different Brazilian populations of Lutzomyia longipalpis (Lutz & Neiva) (Diptera: Psychodidae)

First isolation of microorganisms from the gut diverticulum of Aedes aegypti (Diptera: Culicidae): new perspectives for an insect-bacteria association

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