Bacteremia in patients with ventilator-associated pneumonia is associated with increased mortality: A study comparing bacteremic vs. nonbacteremic ventilator-associated pneumonia*

Ağbaht, Kemal; Dı́az, Emili; Muñoz, Emma; Lisboa, Thiago; Gómez, Frederic; Depuydt, Pieter; Blot, Stijn; Rello, Jordi

doi:10.1097/01.ccm.0000277042.31524.66

Cited by 92 publications

(78 citation statements)

References 37 publications

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“…20 The mortality rate doubles if pneumonia is associated with bacteremia. [21][22][23][24] In our study, bacteremia occurred in 15% of patients with pneumonia, a rate that is equivalent to the general population. 24 The mortality rate among our patients with staphylococcal pneumonia, however, was only 9% (6 of 66) within 30 days from the onset of disease, which was similar for patients with and without bacteremia.…”

Section: Discussionmentioning

confidence: 75%

Staphylococcus aureus infections in the early period after lung transplantation: Epidemiology, risk factors, and outcomes

Shields

Clancy

Minces

et al. 2012

The Journal of Heart and Lung Transplantation

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Section: Discussionmentioning

confidence: 75%

Staphylococcus aureus infections in the early period after lung transplantation: Epidemiology, risk factors, and outcomes

Shields

Clancy

Minces

et al. 2012

The Journal of Heart and Lung Transplantation

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“…7 These striking differences in fatality rates can be explained by differences in study methods (eg matching criteria), target population (eg, age, immune status), causative microorganisms and their antibiotic susceptibility patterns, and appropriateness of antimicrobial therapy. [8][9][10][11][12][13] Other issues that might affect outcome in VAP patients, such as the role of specific nursing protocols, the value of advanced nurse practitioners in the treatment of VAP, compliance with guidelines of the Surviving Sepsis Campaign, and so on, have not been studied extensively.…”

Section: Methodsmentioning

confidence: 99%

Patient to Nurse Ratio and Risk of Ventilator-Associated Pneumonia in Critically Ill Patients

Blot

Llauradó-Serra²,

Koulenti³

et al. 2010

American Journal of Critical Care

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Objective To determine how the patient to nurse ratio affects risk for ventilator-associated pneumonia. Methods Data from an earlier study in 27 intensive care units in 9 European countries were examined in a secondary analysis. The initial cohort included 2585 consecutive patients who had mechanical ventilation (1) after admission for treatment of pneumonia or (2) for more than 48 hours irrespective of the diagnosis at admission. In units with variable staffing levels, the highest patient to nurse ratio in a 24-hour period was considered. Patients from 6 units that did not provide data on nurse staffing levels were excluded from the analysis. Results Ventilator-associated pneumonia developed in 393 of the 1658 patients (23.7%) in the secondary cohort. In units with patient to nurse ratios of 1 to 1, 2 to 1, 2.5 to 1, and 3 to 1, rates were 9.3%, 25.7%, 18.7%, and 24.2%, respectively (P = .003). Rates were significantly lower (P = .002) in units with a ratio of 1 to 1 (9.3%) than in units with a ratio of more than 1 patient to 1 nurse (24.4%). After adjustments for confounding covariates, ratios of more than 1 patient to 1 nurse were no longer associated with increased risk for ventilator-associated pneumonia. Conclusions A patient to nurse ratio of 1 to 1 appears to be associated with a lower risk for ventilator-associated pneumonia, but after adjustments for confounding covariates, the difference is not significant.

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“…ICUacquired infections account for substantial morbidity and mortality. [22][23][24][25] In addition, they contribute to a substantial economic burden mostly by increasing the length of hospitalization. 26,27 The deleterious impact of infections is greater when they are caused by multidrug-resistant pathogens or fungal species.…”

Section: Infection and Sepsismentioning

confidence: 99%

Insights and Advances in Multidisciplinary Critical Care: A Review of Recent Research

Blot

Afonso

Labeau

2014

American Journal of Critical Care

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The intensive care unit is a work environment where superior dedication is pivotal to optimize patients' outcomes. As this demanding commitment is multidisciplinary in nature, it requires special qualities of health care workers and organizations. Thus research in the field covers a broad spectrum of activities necessary to deliver cutting-edge care. However, given the abundance of research articles and education activities available, it is difficult for modern critical care clinicians to keep up with the latest progress and innovations in the field. This article broadly summarizes new developments in multidisciplinary intensive care, providing elementary information about advanced insights in the field by briefly describing selected articles bundled in specific topics. Issues considered include cardiovascular care, monitoring, mechanical ventilation, infection and sepsis, nutrition, education, patient safety, pain assessment and control, delirium, mental health, ethics, and outcomes research.

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Bacteremia in patients with ventilator-associated pneumonia is associated with increased mortality: A study comparing bacteremic vs. nonbacteremic ventilator-associated pneumonia*

Abstract: B-VAP occurs later during intensive care unit stay, is more frequent in previously hospitalized patients, is more often caused by methicillin-resistant S. aureus, and is independently associated with increased intensive care unit mortality.

Cited by 92 publications

References 37 publications

Staphylococcus aureus infections in the early period after lung transplantation: Epidemiology, risk factors, and outcomes

Staphylococcus aureus infections in the early period after lung transplantation: Epidemiology, risk factors, and outcomes

Patient to Nurse Ratio and Risk of Ventilator-Associated Pneumonia in Critically Ill Patients

Insights and Advances in Multidisciplinary Critical Care: A Review of Recent Research

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