Bacteremia Following Nasolacrimal Duct Probing

Ganguly, Anasua; Ali, Mohammad Javed; Padmaja, Kanne; Sharma, Savitri; Vemu, Lakshmi; Naik, Milind N.

doi:10.1097/iop.0000000000000403

Cited by 13 publications

(2 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…H. influenzae and S. pneumoniae were reported to be prevalent bacteria in CNLDO patients with a wider range of age (Table 3 ), both pathogens can induce bacteremia after lacrimal probing [ 29 , 30 ], and S. pneumoniae can cause severe endophthalmitis following glaucoma or cataract surgeries [ 31 , 32 ]. Neisseriae species are part of the normal flora in respiratory system.…”

Section: Discussionmentioning

confidence: 99%

Lacrimal sac bacteriology and susceptibility pattern in infants with congenital nasolacrimal duct obstruction in the 1st year of life: a cross-sectional study

et al. 2020

View full text Add to dashboard Cite

Background Congenital nasolacrimal duct obstruction (CNLDO) is one of the main causes of epiphora in infants, and antibiotics are usually used as a conservative therapy in the first year. Yet, little is known about the bacteriology of the occluded lacrimal drainage system in this group of patients. The aim of this study was to evaluate the microbiology of lacrimal sac (LS) in Chinese children with CNLDO in their first year of life. Methods Patients with CNLDO between May 1, 2017 and August 31, 2018 at a tertiary care children’s hospital were enrolled. The study recruited infants who received lacrimal probing under 1 year old, and refluxed discharge from LS was collected. Samples were cultured and susceptibility test was performed for positive culture. Results Thirty-two patients with CNLDO were included. The ratio of male to female was 23:9. The mean age was 6.7 ± 2.4 (1.7–12) months. Positive cultures was identified in 87.5% of the sample, and presented 38 strains of bacteria. Mixed infection was identified in 10 (31.3%) children. Gram-positive bacteria accounted for 60.5% of all the strains, with Streptococcus (50%) being the most frequent species, whereas Haemophilus (21.1%) and Neisseriae (13.2%) were most common isolates for Gram-negative organisms. Methicillin-resistant Staphylococcus aureus (MRSA) was detected in 2 infants whose symptoms resolved by a routine probing. No difference of bacteriology pattern was detected between patients under 6 months old and those beyond. The pathogens were highly sensitive to chloramphenicol (88%) and levofloxacin (84%), but resistant to erythromycin (40%) and sulfamethoxazole (32%). Conclusions Infants with CNLDO under 1 year of age presented predominance of Streptococcus as Gram-positive organism, and Haemophilus as Gram-negative organism. Levofloxacin was an active topical antibiotic agent with few chance of resistance especially for Chinese children. These findings could help clinicians choose optimal medicine for CNLDO as the conservative treatments.

show abstract

Section: Discussionmentioning

confidence: 99%

Lacrimal sac bacteriology and susceptibility pattern in infants with congenital nasolacrimal duct obstruction in the 1st year of life: a cross-sectional study

et al. 2020

View full text Add to dashboard Cite

show abstract

“…12,28 Baskin et al 4 showed bacteremia in 22.7% of infants and that antibiotic administration 24 hours before probing reduced the chances of repeat probing. Ganguly et al, 29 studied bacteremia in paediatric patients undergoing probing. They recommended that routine probing does not require antibiotic prophylaxis.…”

Section: Discussionmentioning

confidence: 99%

Congenital Nasolacrimal Duct Obstruction Update Study (CUP Study): Paper 4—Infantile Acute Dacryocystitis (InAD)—Presentation, Management, and Outcomes

Bothra

Ali

2021

Ophthalmic Plastic &Amp; Reconstructive Surgery

Self Cite

View full text Add to dashboard Cite

Purpose: To study the presentation, management, and outcomes of infantile acute dacryocystitis. Methods: Retrospective study of infants diagnosed with acute dacryocystitis over a period from June 2016 to December 2019. Data collected include demographics, clinical history, presenting features, management, complications, and outcomes. Treatment provided was intensive medical care followed by early probing under endoscopic guidance. Further interventions, where needed, were performed based on intraoperative findings during probing. Successful outcomes were defined as resolution of infection, subjective relief from epiphora, and anatomical patency determined by a normal fluorescein dye disappearance test. Results: Twenty-seven eyes of 27 infants were analyzed during the study period. The mean age of infants was 3.26 months, and males were more affected than females (male:female 15:12). The mean duration of symptoms was 4.66 weeks, with 96% (26/27) presenting with symptoms of redness, watering, discharge, and swelling. Preseptal cellulitis was seen in 74% (20/27) infants, lacrimal abscess in 67% (18/27) infants, and lacrimal fistula in 37% (10/27). Most infants had complex congenital nasolacrimal duct obstruction (62%, 13/27), of which 7 also had intranasal cysts. One infant successfully underwent endoscopic dacryocystorhinostomy. At a mean follow-up period of 7.95 months, successful outcomes were observed in 90.4% (19/21) infants. The 2 failed cases were complex congenital nasolacrimal duct obstruction with associated sac diverticula and are scheduled for an endoscopic dacryocystorhinostomy. Conclusion: Infantile acute dacryocystitis is a distinct clinical entity. The outcomes of systemic antibiotics and early probing are excellent.

show abstract

Canalicular Obstructions and Management

Enghelberg

Burkat

2019

Oculofacial, Orbital, and Lacrimal Surgery

View full text Add to dashboard Cite

Bacteremia Following Nasolacrimal Duct Probing

Cited by 13 publications

References 15 publications

Lacrimal sac bacteriology and susceptibility pattern in infants with congenital nasolacrimal duct obstruction in the 1st year of life: a cross-sectional study

Lacrimal sac bacteriology and susceptibility pattern in infants with congenital nasolacrimal duct obstruction in the 1st year of life: a cross-sectional study

Congenital Nasolacrimal Duct Obstruction Update Study (CUP Study): Paper 4—Infantile Acute Dacryocystitis (InAD)—Presentation, Management, and Outcomes

Canalicular Obstructions and Management

Contact Info

Product

Resources

About