BacSC: A general workflow for bacterial single-cell RNA sequencing data analysis
Johannes Ostner,
Tim Kirk,
Roberto Olayo-Alarcon
et al.
Abstract:Bacterial single-cell RNA sequencing has the potential to elucidate within-population heterogeneity of prokaryotes, as well as their interaction with host systems. Despite conceptual similarities, the statistical properties of bacterial single-cell datasets are highly dependent on the protocol, making proper processing essential to tap their full potential. We present BacSC, a fully data-driven computational pipeline that processes bacterial single-cell data without requiring manual intervention. BacSC perform… Show more
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