Backache could be an indication of multiple myeloma: An unusual case report

Abstract

Unusual presentation of multiple myeloma (MM) poses a diagnostic dilemma. The objective of this case report is to document the unique presentation of MM and to highlight the importance of backache which could be the only indicator for the diagnosis of MM. Although a history of trauma in the past is present in this case, but there is no molecular basis/evidence to declare trauma as a risk factor for MM. It can be concluded that the patients with backache should be thoroughly investigated to rule out any possibility of malignant disease process.Bangladesh Journal of Medical Science Vol.17(2) 2018 p.311-315

Primary Plasma Cell Leukaemia with Lambda Light Chain secretion and Chromosomal abnormalities presenting as hyperleukocytosis - A case report.

“…A higher proportion of light chain-only, Ig E, and IgD myelomas present as PCL in serum immunofixation studies when compared to IgG or IgA myelomas 1 . To detect both lytic bone lesions and extramedullary plasmacytomas, whole-body imaging with magnetic resonance imaging (MRI), computerised tomography (CT), or 18F-fluorodeoxyglucose positron emission tomography (PET)/CT should be performed 7 A specific treatment for pPCL is not well defined. Combination chemotherapy with immunomodulatory agents such as bortezomib, proteasome inhibitors, lenidomide, and steroids such as dexamethasone, followed by high-dose melphalan improves prognosis in pPCL.…”