Back Cover: Macromol. Biosci. 12/2014

Abstract

Back Cover: A multifunctional folate targeted ribotoxinpolymeric/lipid nanoformulation is used to image and specifically arrest the proliferation tendencies of human glioblastoma by additionally suppressing the anti‐apoptotic survivin and membrane interaction vinculin proteins. The formulation presented by D. S. Kumar and co‐workers http://doi.wiley.com/10.1002/mabi.201400248 could be used as a potent theranostic vector system for diverse cancer subtypes.

Multi-stimuli responsive Cu2S nanocrystals as trimodal imaging and synergistic chemo-photothermal therapy agents

“…11-13 Initially, nanoparticles (NPs) for therapeutics were formulated solely to transport drugs to lesion sites without any added functionalities. 14-16 However recent advances in nanotechnology have nurtured the engineering of precision nanomaterials with multiple, discrete function-related components integrated into a single nanosystem for efficient biomedical applications.…”

“…[7][8][9][10] The main objectives of nanotechnology in medicine, nanomedicine, for cancer therapy include the specific identification of cancerous cells from the vast number and diversity of normal cells surrounding the tumor, augmenting the therapeutic ability of the drugs, and tracing the location of the drug/cargo inside the biological system. [11][12][13] Initially, nanoparticles (NPs) for therapeutics were formulated solely to transport drugs to lesion sites without any added functionalities. [14][15][16] However, recent advances in nanotechnology have nurtured the engineering of precision nanomaterials with multiple, discrete function-related components integrated into a single nanosystem for efficient biomedical applications.…”

Functionalized Carbon Nanowalls as Pro-Angiogenic Scaffolds for Endothelial Cell Activation

“…Cell Preparation for SEM Analysis. Cell preparation for SEM evaluation was performed according to previous report 29 with modifications. Cells (on respective substrates) were prefixed in 0.1% glutaraldehyde in culture media for 5 min.…”

FITC/suramin harboring silica nanoformulations for cellular and embryonic imaging/anti-angiogenic theranostics

“…Application of such multifunctional nanomaterials and their prospective efficiencies are being testified at a stride never seen before with a huge repository of data accumulating in recent years. [6][7][8][9] Silica NPs exhibit certain advantages such as extended blood circulation times due to their hydrophilicity, versatile surface functionalization options, biocompatibility and ease of costeffective large-scale synthesis. [10][11][12] Most of the recent reports on silica NPs have revolved around monodisperse 80-120 nm particles.…”