Abstract:Alcohol is the solution: The potential of many 18F‐labeled (hetero)aromatics for positron emission tomography (PET) remains underexploited, so the development and optimization of radiolabeling procedures remains a research area of considerable interest. It is shown herein that alcohol‐containing solvent systems give rise to unexpectedly enhanced copper‐mediated aromatic 18F‐labeling, enabling rapid radiolabeling of a broad scope of boronic and stannyl substrates under general reaction conditions. Among others,… Show more
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