Back Cover: A Rationally Designed Connector for Assembly of Protein‐Functionalized DNA Nanostructures (ChemBioChem 12/2016)

Abstract

The back cover picture shows “HOB Art”, an artistic depiction of a DNA origami nanostructure decorated with six HOB proteins. HOB is a halo‐based oligonucleotide‐binder protein with a rationally engineered binding interface to attain extraordinarily high reaction rates in the covalent ligation with chlorohexyl‐modified DNA. More information about the art of HOBbing proteins with DNA can be found in the communication by C. M. Niemeyer et al. on page 1102 in Issue 12, 2016 (DOI: 10.1002/cbic.201600039).