Bacitracin irrigation leading to anaphylaxis and cardiovascular collapse in the ambulatory surgery center setting

Burnett, Garrett; Meisner, J.; Hyman, Jaime B.; Levin, Emily J.

doi:10.1016/j.jclinane.2018.01.008

Cited by 4 publications

(2 citation statements)

References 5 publications

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“…This fact is explained by the particular chemical structure, whose R1 side-chain are different from other beta-lactams [45]. Bacitracin was responsible for anaphylaxis and cardiovascular collapse in an ambulatory surgery center setting within 1 min after irrigation with bacitracin solution, after removal of breast implants in situ, for bilateral breast implant exchange [46]. Antibiotics were the second cause of anaphylactic reactions during anesthesia in a survey that received answers from 242 anesthesiologists form India in 2017 [47].…”

Section: Antibioticsmentioning

confidence: 99%

Could Artificial Intelligence Prevent Intraoperative Anaphylaxis? Reference Review and Proof of Concept

et al. 2022

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Drugs and various medical substances have been used for many decades to diagnose or treat diseases. Procedures like surgery and anesthesia (either local or general) use different pharmacological products during these events. In most of the cases, the procedure is safe and the physician performs the technique without incidents. Although they are safe for use, these substances (including drugs) may have adverse effects, varying from mild ones to life-threatening reactions in a minority of patients. Artificial intelligence may be a useful tool in approximating the risk of anaphylaxis before undertaking a medical procedure. This material presents these undesirable responses produced by medical products from a multidisciplinary point of view. Moreover, we present a proof of concept for using artificial intelligence as a possible guardship against intraoperative anaphylaxis.

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Section: Antibioticsmentioning

confidence: 99%

Could Artificial Intelligence Prevent Intraoperative Anaphylaxis? Reference Review and Proof of Concept

et al. 2022

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“…They issued this request because bacitracin for injection is no longer used to treat the indicated conditions on the label (ie, pneumonia, empyema) and because other products are available to treat these infections without the risk for nephrotoxicity and anaphylactic reactions 1 . Clinicians have published multiple case reports of patients who experienced anaphylactic reactions to intraoperative bacitracin irrigation in surgical wounds 2‐4 . Although bacitracin for injection is frequently used to irrigate surgical wounds, this practice is considered an off‐label use of the medication.…”

Section: Discontinuing the Use Of Intraoperative Bacitracin Irrigationmentioning

confidence: 99%

Clinical Issues—February 2021

Wood¹

2021

AORN Journal

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THIS MONTH Moving the surgical lights over a sterile field Key words: surgical lights, light handles, sterile field contamination, surgical site infection (SSI). Transport stretchers in the OR Key words: transport stretcher, bed linens, cross-contamination, sterile field, infectious disease. Using positive‐pressure ORs for patients who require airborne precautions Key words: airborne precautions, positive‐pressure airflow, positive‐pressure OR, anteroom. Discontinuing the use of intraoperative bacitracin irrigation Key words: bacitracin for injection, antibiotic irrigation, antimicrobial irrigation, surgical site infection (SSI).

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Bacitracin

2018

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Bacitracin irrigation leading to anaphylaxis and cardiovascular collapse in the ambulatory surgery center setting

Cited by 4 publications

References 5 publications

Could Artificial Intelligence Prevent Intraoperative Anaphylaxis? Reference Review and Proof of Concept

Could Artificial Intelligence Prevent Intraoperative Anaphylaxis? Reference Review and Proof of Concept

Clinical Issues—February 2021

Bacitracin

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