Bacillus Calmette–Guerin (BCG) for Urothelial Carcinoma of the Bladder

Kresowik, Timothy P.; Griffith, Thomas S.

doi:10.1002/9780470626528.ch3

Search citation statements

Order By: Relevance

Paper Sections

Select...

Up-regulation Of the Immune System1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2013

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

(1 citation statement)

References 72 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Immunotherapy with Mycobacterium bovis Bacillus Calmete-Guerin (BCG) is used in clinical practice to treat/prevent the recurrence of superficial bladder cancer (Kresowik and Griffith 2010). The choice of a BCG based therapy depends upon the location and grade of the tumor and follows the recommendations described by several organizations, such as the ESMO Clinical Practice Guidelines (Bellmunt et al 2010).…”

Section: Up-regulation Of the Immune Systemmentioning

confidence: 99%

Engineering of bacterial strains and their products for cancer therapy

Bernardes

Chakrabarty

Fialho

2013

Appl Microbiol Biotechnol

View full text Add to dashboard Cite

The use of live bacteria in cancer therapies offers exciting possibilities. Nowadays, an increasing number of genetically engineered bacteria are emerging in the field, with applications both in therapy and diagnosis. In parallel, purified bacterial products are also gaining relevance as new classes of bioactive products to treat and prevent cancer growth and metastasis. In the first part of the article, we review the latest findings regarding the use of live bacteria and products as anti-cancer agents, paying special attention to immunotoxins, proteins, and peptides. In particular, we focus on the recent results of using azurin or its derived peptide as anticancer therapeutic agents. In the second part, we discuss the challenges of using metagenomic techniques as a distinctive approach for discovering new anti-cancer agents from bacterial origin.

show abstract

Section: Up-regulation Of the Immune Systemmentioning

confidence: 99%