Bacillus amyloliquefaciens 40 regulates piglet performance, antioxidant capacity, immune status and gut microbiota

Jiang, Zipeng; Su, Weixu; Li, Wentao; Wen, Chaoyue; Du, Shuai; He, Huan; Gong, Tao; Wang, Xinxia; Wang, Yizhen; Jin, Mingliang; Lu, Zeqing

doi:10.1016/j.aninu.2022.09.006

Cited by 10 publications

(5 citation statements)

References 81 publications

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“…Desulfovibrio is a sulfate-reducing bacterium, it was positively associated with serum immune-related GLOB in this study, probably due to its bioremedial potential (Rowan et al, 2010). In the gut of pigs, Desulfovibrio was also positively associated with the health state and growth performance (Jiang et al, 2022). Oscillospira are widely found in the digestive tracts of herbivores (Mackie et al, 2003;Ren et al, 2017), and from metagenomic and metabolic characterization, this organism was able to mediate butyrate kinasemediated, which was indicated that Oscillospira are butyrate producers.…”

Section: Can Improvesupporting

confidence: 55%

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Assessment of the influence on Hypsizygus marmoreus stem waste as a sustainable alternative to corn in Holdobagy geese dietary

Wang

et al. 2023

Front. Sustain. Food Syst.

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The processing of edible mushrooms generates a large amount of mushroom residue. How to handle this mushroom residue in a way that avoids environmental pollution and maximizes effective utilization is a current issue that needs to be explored. This study aimed to investigate the effects of substituting dietary corn with Hypsizygus marmoreus mushroom stem waste (HSW) in the diet of geese. The control group was fed with a basal diet (BD), and the other groups were fed the basal diet to which 12% (HSW12 group), 24% (HSW24 group), or 32% (HSW32 group) of HSW were added to replace the equivalent proportion of corn. The test lasted 28 days. The results showed that the average daily feed intake (ADFI) of the HSW12 and HSW24 groups at 35–49 d, and the HSW12 and HSW32 groups at 35–63 d, was significantly higher compared to the BD group (p<0.05). The average daily gain (ADG) of the HSW12 group was significantly higher than BD at 35–49 d (p<0.05), but there was no significant difference in the feed/gain (F/G) among the groups. The levels of serum total protein (TP), albumin (ALB), globulin (GLOB), glutathione peroxidase (GSH-Px), and catalase (CAT) in HSW24 group were significantly higher than those in the BD group (p<0.05). Total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), and malondialdehyde (MDA) decreased significantly, and there were no significant differences in carcass traits and meat quality. As 24% HSW supplementation had the best overall effect on the growth performance, serum biochemical indicators, meat quality, and carcass traits of geese, gut microbiota analysis was only performed on this group. The microbiota α-diversity of the cecum and ileum did not differ significantly between the BD and HSW24 groups. Principal coordinate analysis (PCoA) indicated that the difference in the cecum was significant in the β-diversity (p<0.05). Short chain fatty acid-producing bacteria and decomposing protein and carbohydrate bacteria (Prevotella) were enriched in the cecum in the HSW24 group. Gut immune regulating and nutritional bacteria, Lactococcus and Bacillus, respectively, were enriched in the ileum in HSW24 group. Spearman’s analysis indicated that Bacillus, Prevotella, and Clostridium were positively associated with serum protein and lipid metabolism. These results indicate that 24% HSW substitution of corn could improve goose serum ALB and fat metabolism, and increase serum antioxidant capacity, which may becaused by the improvement of goose cecal microbiota.

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Section: Can Improvesupporting

confidence: 55%

“…Bacillus has a variety of probiotic functions, similar to Bacillus amyloliquefaciens and Bacillus subtilis, which are widely used as probiotics in animal husbandry (Jiang et al, 2022;. Bacillus can induce Oscillospira to become a dominant genus (Keerqin et al, 2021) and can be used to treat diarrhea in pigs (Jinno et al, 2022).…”

Section: Can Improvementioning

confidence: 99%

Assessment of the influence on Hypsizygus marmoreus stem waste as a sustainable alternative to corn in Holdobagy geese dietary

Wang

et al. 2023

Front. Sustain. Food Syst.

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“…Reportedly, the relative abundance of Erysipelotrichaceae in piglet cecum contents of digesta was negatively correlated with the expression of inflammatory factors [ 59 ]. Phascolarctobacterium was positively correlated with serum antioxidant capacity, and negatively correlated with serum pro-inflammatory cytokines in piglets [ 60 ]. However, the effect of Holdemanella is controversial.…”

Section: Discussionmentioning

confidence: 99%

The Effect of an Essential Oil Blend on Growth Performance, Intestinal Health, and Microbiota in Early-Weaned Piglets

Shao

Peng²,

et al. 2023

Nutrients

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Essential oils (EO) are promising feed additives for their antibacterial, antioxidant, and immune-enhancing abilities with low toxicity. Carvacrol, thymol, and cinnamaldehyde are commonly used to synthesize EO. However, few studies focus on combining these three EO in early-weaned piglets. In the present study, 24 piglets weaned at 21 d of age were randomly divided into 2 groups (6 replicate pens per group, 2 piglets per pen). The piglets were fed a basal diet (the control group) and a basal diet supplemented with 400 mg/kg EO (a blend consisting of carvacrol, thymol, and cinnamaldehyde, the EO group) for 28 days. At the end of the experiment, one piglet per pen was randomly chosen to be sacrificed. Growth performance, hematology, plasma biochemical indices, antioxidant capacity, intestinal epithelial development and immunity, colonic volatile fatty acids (VFA), and microbiota were determined. The results indicated that the diet supplemented with EO significantly improved average daily feed intake (ADFI, p < 0.01) and average daily gain (ADG, p < 0.05) in the day 0 to 28 period. EO supplementation led to a significant decrease in plasma lysozyme (p < 0.05) and cortisol levels (p < 0.01). Additionally, EO significantly promoted jejunal goblet cells in the villus, jejunal mucosa ZO-1 mRNA expression, ileal villus height, and ileal villus height/crypt depth ratio in piglets (p < 0.05). The ileal mucosal TLR4 and NFκB p-p65/p65 protein expression were significantly inhibited in the EO group (p < 0.05). Colonic digesta microbiota analysis revealed that bacteria involving the Erysipelotrichaceae family, Holdemanella genus, Phascolarctobacterium genus, and Vibrio genus were enriched in the EO group. In conclusion, these findings indicate that the EO blend improves ADG and ADFI in the day 0 to 28 period, as well as intestinal epithelial development and intestinal immunity in early-weaned piglets, which provides a theoretical basis for the combined use of EO in weaned piglets.

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“…Faced with this controversial issue, some countries and regions have introduced restrictive policies on antibiotics added to feed, and alternatives to antibiotics have received increasing attention [9,10]. Probiotics such as Lactobacillus, Bacillus subtilis, and yeast are able to remodel the gut microbiota, alleviate ecological dysbiosis of the intestinal flora, attenuate intestinal inflammation [11][12][13], and improve immune, antioxidant, and production performance [14][15][16]; thus, fermented feed containing probiotics can be used to replace antibiotics in livestock feed.…”

Section: Introductionmentioning

confidence: 99%

Effects of Probiotic-Fermented Feed on the Growth Profile, Immune Functions, and Intestinal Microbiota of Bamei Piglets

Zhang,

Yang,

et al. 2024

Animals

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Purebred Bamei piglets present problems, including slow growth, respiratory disease, and post-weaning stress. This study investigated the effects of Lactobacillus plantarum QP28-1- and Bacillus subtilis QB8-fermented feed supplementation on the growth performance, immunity, and intestinal microflora of Bamei piglets from Qinghai, China. A total of 48 purebred Bamei piglets (25 days; 6.8 ± 0.97 kg) were divided into the following four groups for a 28-day diet experiment: basal feed (CK); diet containing 10% Lactobacillus plantarum-fermented feed (L); diet containing 10% Bacillus subtilis-fermented feed (B); and diet containing a mixture of 5% Lactobacillus plantarum + 5% Bacillus subtilis-fermented feed (H). The daily weight gain and daily food intake of group H increased (p < 0.05), and the feed/weight gain ratios of the groups fed with fermented feed decreased more than that of the CK group. The levels of three immune factors, namely immunoglobulin (Ig)M, IgG, and interferon-γ, were higher (p < 0.05), whereas those of tumor necrosis factor-α, interleukin (IL)-1β, and IL-6 were lower (p < 0.05) in the fermented feed groups than in the CK group. Total protein was higher (p < 0.05), while urea nitrogen, total cholesterol and triglycerides were lower (p < 0.05) in the mixed-fermented feed group than in the CK group. Analysis of the gut microbiota showed that the addition of fermented feed increased the α-diversity of the gut microbiota, increasing the abundances of probiotics including Lactobacillus, Muribaculaceae, Ruminococcaceae, Prevotellaceae, and Rikenellaceae. Additionally, correlation analysis demonstrated that several of these probiotic bacteria were closely related to serum immunity. In conclusion, fermented feed supplementation rebuilt the intestinal microbiota of Bamei piglets, thereby reducing the feed/weight ratio, improving feed intake, and enhancing immunity.

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Bacillus amyloliquefaciens 40 regulates piglet performance, antioxidant capacity, immune status and gut microbiota

Cited by 10 publications

References 81 publications

Assessment of the influence on Hypsizygus marmoreus stem waste as a sustainable alternative to corn in Holdobagy geese dietary

Assessment of the influence on Hypsizygus marmoreus stem waste as a sustainable alternative to corn in Holdobagy geese dietary

The Effect of an Essential Oil Blend on Growth Performance, Intestinal Health, and Microbiota in Early-Weaned Piglets

Effects of Probiotic-Fermented Feed on the Growth Profile, Immune Functions, and Intestinal Microbiota of Bamei Piglets

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