Bacillary Layer Detachment (BALAD) in Macular Choroidal Metastasis of a Low-grade Rectal Adenocarcinoma

Bacillary layer detachment with malignant choroidal tumors: a case series

“…Studies on BALAD detection have majorly focused on its prognostic implications in macular neovascularization (reported incidence range, 4.5 − 7.4%) [ 2 – 5 , 17 ] and inflammatory choroidal pathologies such as Vogt-Koyanagi-Harada disease (reported incidence, 94.9%) [ 6 , 18 ]. Case reports or small case series have also described BALAD with other inflammatory ocular pathologies as acute posterior multifocal placoid pigment epitheliopathy [ 13 , 19 , 20 ] and serpiginous-like choroidopathy associated with tuberculosis [ 12 , 21 ], infiltrative ones such as unilateral diffuse uveal melanocytic proliferation [ 15 ] and choroidal metastasis [ 14 ], degenerative lesions as macular telangiectasia that was associated with acute leakage and hemorrhage [ 22 ], and blunt eye trauma (reported incidence, 8% [ 7 ]). The incidence of BALAD with most of these pathologies is less recognized owing to the lack of structured analyses.…”

“…Isolated case reports have described BALAD with other ocular pathologies, where the incidence and spectrum of the finding is less clear, including blunt eye trauma [ 7 , 8 ], the pachychoroid spectrum of disorders [ 9 , 10 ], choroidal tuberculous granuloma [ 11 ], and other causes of choroiditis [ 12 , 13 ]. Two case reports [ 10 , 14 ] described the occurrence of BALAD with choroidal metastasis, and another one [ 15 ] described it with the rare entity of unilateral diffuse uveal melanocytic proliferation. Herein, we study the incidence and characteristics of BALAD occurring with the two most common choroidal malignancies: choroidal metastasis and choroidal melanoma.…”