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Abstract

Background: The female breast is one of the most commonly biopsied tissues because of the myriads of diseases and lesions that arise from it. Timely and accurate diagnosis of a breast lump can not only alleviate anxiety but also early intervention can be lifesaving. In India, breast cancer forms the second most common malignancy after cervical cancer and is detected in 20/1,00,000 women. Objectives: To study the clinic pathological aspect and histopathological patterns of neoplastic and non neoplastic breast lesions. Material and Method: A prospective study was carried out on 218 cases in tertiary care institute at S.R.T.R. GMC Ambajogai. Breast lesions were evaluated over a period of one and half year. The specimen were routinely processed and stained with Heamatoxylin and Eosin (HandE) and examined microscopically. Cases included in this study were of non-neoplastic and neoplastic breast lesions which included incisional biopsies, lumpectomy and all types of mastectomy specimens from surgical department at rural hospital. Results: Among 218 cases, 181 were neoplastic and 37 cases were non neoplastic. Majority of cases were fibroadenoma i.e. 118 cases. Invasive carcinoma-no special type (NST) was the most common malignant neoplasm i.e. 43 cases. The most common inflammatory nonneoplastic lesion was mastitis with 14 cases and benign epithelial lesion was fibrocystic change. Most of the breast tumors were noted in left breast and involved upper outer quadrant most frequently.The nonneoplastic lesions were common in third decade, benign tumour in second and third decades and malignant tumours were common in sixth decades. Conclusions: This study highlights the importance of histopathological examination in breast lumps not only in establishing the final diagnosis, but also in predicting the prognosis of breast neoplasms.