B-Vitamin Intake from Diet and Supplements and Breast Cancer Risk in Middle-Aged Women: Results from the Prospective NutriNet-Santé Cohort

Egnell, Manon; Fassier, Philippine; Lécuyer, Lucie; Zelek, Laurent; Vasson, Marie‐Paule; Herçberg, Serge; Latino‐Martel, Paule; Galán, Pilar; Deschasaux, Mélanie; Touvier, Mathilde

doi:10.3390/nu9050488

Cited by 29 publications

(17 citation statements)

References 44 publications

(104 reference statements)

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“…Vitamin D is important in many physiological processes, is predominantly obtained through UVB radiation, and has been ascribed an important role in calcium homeostasis, bone health, and anti-cancer activity [118]. Some research has been published documenting a protective role of vitamin D against breast cancer [119, 120]. Moreover, higher levels of vitamin D may be associated with improved survival [121].…”

Section: Dietary Factors and Nutrition In Breast Cancer Riskmentioning

confidence: 99%

Obesity, Dietary Factors, Nutrition, and Breast Cancer Risk

Seiler

Chen

Brown

et al. 2018

Curr Breast Cancer Rep

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Purpose of Review To synthesize the critical role of obesity-associated inflammation, dietary factors, and nutrition in determining breast cancer risk. Recent Findings Obesity-associated inflammation is strongly linked to breast cancer risk and progression, largely via two processes: inflammatory pathways and dysregulated metabolism. Cytokine production in excess adipose tissues creates a chronic inflammatory microenvironment, which favors tumor development. Lifestyle factors, including diet, have long been recognized as important determinants of breast cancer risk and mortality. Summary Obesity increases the risk of developing breast cancer in both pre- and postmenopausal women and also negatively affects breast cancer recurrence and survival. Poor dietary habits characterized by the high intake of refined starches, sugar, and both saturated and trans-saturated fats, as well as the low intake of omega-3 fatty acids, natural antioxidants, and fiber, modulate inflammation and, thereby, appear to be linked to increased risk of breast cancer and mortality.

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Section: Dietary Factors and Nutrition In Breast Cancer Riskmentioning

confidence: 99%

Obesity, Dietary Factors, Nutrition, and Breast Cancer Risk

Seiler

Chen

Brown

et al. 2018

Curr Breast Cancer Rep

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“…Among the vitamins and minerals, only carotenoids, folate, calcium, vitamin D, lycopene, and vitamin C have been associated with a lower risk of breast cancer (World Cancer Research Fund Panel (Potter JD Chair), 1997;Dorgan et al, 1998;Hulten et al 2001;Sato et al, 2002;Egnell et al, 2017). Although, the vitamins intake was statistically significant between the groups in our study, our patients and controls were not taking enough doses to be effective as regular use of such micronutrients after food is alien to our community.…”

Section: Discussionmentioning

confidence: 99%

“…Analyses of prospective studies suggest that women with low folate intakes and greater alcohol consumption ran a greater risk for breast cancer than non-drinkers with normal folate intakes (Sellers et al, 2002;Zhang et al, 1999). In a studies involving a large cohort of normal women taking vitamin A, B, C and E supplements, followed-up for 2 decades, it was discovered that taking large doses of thiamine and vitamins C and E did reduce the risk of breast cancer but low intake of vitamin A increased the risk of breast cancer (Egnell et al, 2017;Hunter et al, 1993).…”

Section: Discussionmentioning

confidence: 99%

The influence of life behaviour, diet, physical activities on the incidence of breast cancer among women attending Obafemi Awolowo University Teaching Hospital Complex, Ile-Ife

Arowolo¹,

Olasehinde²,

Oyekunle³

et al. 2018

J. Cancer Res. Exp. Oncol.

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The aetiopathogenesis of cancer has been linked to life behaviour in a significant percentage of cases. Overweight, sedentary lifestyle, smoking and the excessive use of alcohol have been shown to play important roles. This study is aimed at determining the effect of life behavioural patterns and diets in the incidence of breast cancer in Nigerians population. A prospective case-controlled study of 125 breast cancer patients and 89 normal were recruited in Obafemi Awolowo University Teaching Hospital Complex, (OAUTHC), Ile-Ife, Nigeria. Questionnaire was administered to determine life behavioural patterns and nutritional habits. The variables on nutrition items were pooled to form 23 aggregate variables renamed "total variables" and exposure to endogenous estrogens was calculated. The means age in the patient and control groups were 45.9±10.4 and 44.5±15.2 years, respectively. A significantly higher number of patients in the breast cancer group had at least one previous abortion compared to the control group. The two groups have similar contraceptive use history and mean body mass index (BMI). 14 derived variables on univariate analysis were found to be significant, but only four (menarche [p = 0.002], "total beans" [p = 0.003], "total oils" [p = 0.021] and alcohol intake [p = 0.034]) reached statistical significance when subjected to multivariate regression analysis. Most were premenopausal but onsets of menarche were significantly higher among breast cancer patients. The onset of menarche, intake of beans, oils and alcohol may play a role in the incidence of breast cancer.

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“…However, since those studies mainly focused on elucidating clinical predictors of HCC, whether lifestyle habits including smoking and dietary factors affect progression of liver disease after SVR has remained unclear. In addition, as a dietary factor, while vitamin B intake has been reported to have protective effects against the development of cancers at other sites such as breast cancer [18] and colorectal cancer [19], the association with HCC remains unclear. The present study thus aimed to clarify associations between lifestyle habits and liver disease progression using a database of chronic HCV patients established in 2005 and their follow-up data until 2017.…”

Section: Introductionmentioning

confidence: 99%

Lifestyles Associated with Prognosis After Eradication of Hepatitis C Virus: A Prospective Cohort Study in Japan

et al. 2020

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Background: Hepatocellular carcinoma develops in some patients with hepatitis C virus (HCV), even after achieving sustained virological response (SVR). Aims:We examined factors associated with liver disease progression in a prospective cohort study of SVR patients. Methods:Participants were patients who had visited a hospital for clinical follow-up of chronic HCV infection in 2005 and had reached SVR as a result of subsequent antiviral treatment.Baseline information including lifestyle and dietary habits before SVR was collected in 2005 using self-administered questionnaires, and clinical information before SVR was collected from medical records in 2005. Study outcome was liver disease progression such as liver cirrhosis, hepatocellular carcinoma, and/or liver disease-related death after SVR. Proportional hazard models were employed to calculate hazard ratios (HRs) and 95% confidence intervals for each variable.Results: Of 180 SVR patients, 27 patients (15%) showed liver disease progression after SVR: 26 (14%) were diagnosed with liver cirrhosis, two (1%) with hepatocellular carcinoma, and/or one (0.6%) with liver-disease related death. Besides older age at SVR (HR=11.9, P<0.01) and aspartate aminotransferase-to-platelet ratio index score ≥ 1.0 before SVR (HR=2.63, P=0.03), alcohol drinkers before SVR (HR=2.82, P=0.06) was suggested to be associated with liver disease progression after SVR, whereas higher consumption of vitamin B12 before SVR showed a decreased HR for liver disease progression (HR=0.41, P=0.09).Conclusions: Alcohol drinking might be associated with liver disease progression, whereas vitamin B12 intake might have protective effects against liver disease progression after eradication of HCV. Further studies are needed to confirm these findings.

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B-Vitamin Intake from Diet and Supplements and Breast Cancer Risk in Middle-Aged Women: Results from the Prospective NutriNet-Santé Cohort

Cited by 29 publications

References 44 publications

Obesity, Dietary Factors, Nutrition, and Breast Cancer Risk

Obesity, Dietary Factors, Nutrition, and Breast Cancer Risk

The influence of life behaviour, diet, physical activities on the incidence of breast cancer among women attending Obafemi Awolowo University Teaching Hospital Complex, Ile-Ife

Lifestyles Associated with Prognosis After Eradication of Hepatitis C Virus: A Prospective Cohort Study in Japan

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