<b>Ventilation and Heart Rate Response During Exercise in Normals:</b> Relevance for Rate Variable Pacing

Treese, N; MacCarter, Dean; Akbulut, Omar; Coutinho, Mário Sérgio Soares de Azeredo; Baez, Marchena; Liebrich, Andreas; Meyer, Jürgen

doi:10.1111/j.1540-8159.1993.tb01040.x

Cited by 35 publications

(19 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The correlation between heart rate and pulmonary ventilation rate during exercise is high and, while it varies between individuals, a predictable association can be made for an individual once a heart-rate ventilation association equation has been produced [50,51]. The current study did not include exercise testing to provide values for such an equation, however, the intention was to make intra-individual comparison of heart rates between route alterations to estimate if inhaled particle count was determined by PNC rather than pulmonary ventilation level.…”

Section: Discussionmentioning

confidence: 99%

Utility of an alternative bicycle commute route of lower proximity to motorised traffic in decreasing exposure to ultra-fine particles, respiratory symptoms and airway inflammation – a structured exposure experiment

et al. 2013

View full text Add to dashboard Cite

BackgroundBicycle commuting in an urban environment of high air pollution is known to be a potential health risk, especially for susceptible individuals. While risk management strategies aimed to reduce exposure to motorised traffic emissions have been suggested, only limited studies have assessed the utility of such strategies in real-world circumstances.ObjectivesThe potential to lower exposure to ultrafine particles (UFP; < 0.1 μm) during bicycle commuting by reducing proximity to motorised traffic was investigated with real-time air pollution and intermittent acute inflammatory measurements in healthy individuals using their typical higher proximity, and an alternative lower proximity, bicycle commute route.MethodsThirty-five healthy adults (mean ± SD: age = 39 ± 11 yr; 29% female) completed two return trips, one each in the condition of their typical route (HIGH) and a pre-determined alternative route of lower proximity to motorised traffic (LOW); proximity being determined by the proportion of on-road cycle paths. Particle number concentration (PNC) and diameter (PD) were monitored in-commute in real-time. Acute inflammatory indices of respiratory symptoms (as a scalar of frequency from very low to very high / 1 to 5), lung function and spontaneous sputum (for inflammatory cell analyses) were collected immediately pre-commute, and immediately and three hours post-commute.ResultsIn the condition of LOW, compared to in the condition of HIGH, there was a significant decrease in mean PNC (1.91 x e4 ± 0.93 × e4 ppcc vs. 2.95 × e4 ± 1.50 × e4 ppcc; p ≤ 0.001), and the mean frequency of in-commute offensive odour detection (2.1 vs. 2.8; p = 0.019), dust and soot observation (1.7 vs. 2.3; p = 0.038) and nasopharyngeal irritation (1.5 vs. 1.9; p = 0.007). There were no significant differences between LOW and HIGH in the commute distance and duration (12.8 ± 7.1 vs. 12.0 ± 6.9 km and 44 ± 17 vs. 42 ± 17 min, respectively), or other indices of acute airway inflammation.ConclusionsExposure to PNC and offensive odour, and nasopharyngeal irritation, can be significantly lowered when utilising a route of lower proximity to motorised traffic whilst bicycle commuting, without significantly affecting commute distance or duration. This may bring health benefits for both healthy and susceptible individuals.

show abstract

Section: Discussionmentioning

confidence: 99%

Utility of an alternative bicycle commute route of lower proximity to motorised traffic in decreasing exposure to ultra-fine particles, respiratory symptoms and airway inflammation – a structured exposure experiment

et al. 2013

View full text Add to dashboard Cite

show abstract

“…The study group consisted of 60 healthy subjects with a mean age of 45-8 (SD 18-3) years (37 men: 42-2 (16-2) years, body surface area 195-0 (13)(14)(15)(16)(17)(18)(19) cm2; 23 women: 51-6 (20 4) years, body surface area 165-9 (12-1) cm2) who were tested using both peak and low intensity exercise. Informed consent was obtained from all subjects.…”

Section: Study Groupmentioning

confidence: 99%

Oxygen uptake kinetics during low intensity exercise: relevance for rate adaptive pacemaker programming.

Lewalter

Rickli

MacCarter

et al. 1997

Heart

View full text Add to dashboard Cite

Objective-To establish a normal database for oxygen uptake (Vo,) kinetics during low intensity treadmill exercise (LITE) testing, to be used as a guideline for programming rate adaptive pacemakers, and to determine its relation to Vo2 at anaerobic threshold and peak exercise.Design-Vo, kinetics during LITE were compared with Vo2 at anaerobic threshold and at peak exercise. Setting-LITE testing is applicable during ambulatory or hospital care and can even be performed by patients with reduced cardiac capacity. Patients-60 healthy subjects (23 women, 51-6 (SD 20.4) years; 37 men, 42-2 (16.2) years). Interventions-Treadmill exercise testing with "breath by breath" gas exchange monitoring using the LITE protocol for steady state, submaximal exercise, and the ramping incremental treadmill exercise (RITE) protocol for peak exercise. Main outcome measures-Mean response time of Vo2, mean oxygen deficit, and Vo2 at anaerobic threshold (Vo2-AT) and at peak exercise (Vo2-peak) were determined. Results-(1) LITE protocol: mean response time of Vo2 = 35-1 (9.9) s; oxygen deficit = 418-3 (47.9) ml; oxygen deficitlVo2 time index = 54.7 (7.4). (2) RITE protocol: Vo2-AT = 22*1 (5.7) mllkg/min; heart rate at anaerobic threshold = 120-1 (3-6) beats/min; Vo2-peak = 37-6 (10-7) mllkglmin; peak heart rate = 167*8 (19-3) beats/min. The mean response time and oxygen deficitlVo2 time index were significantly correlated to Vo2-peak and Vo2-AT (P < 0'01). Conclusions-Vo2 kinetics calculated in healthy controls may serve as a control database for assessing the rate response programming of pacemakers and its influence on Vo2 during LITE. Because aerobic capacity below the anaerobic threshold is more likely to represent activity in daily life and the kinetics of Vo2 are significantly related to Vo2 at anaerobic threshold and peak exercise, LITE may provide a clinically useful correlate to peak exercise testing.

show abstract

“…However, since ventilation is tightly linked to heart rate during exercise (Treese et al, 1993) we thought that near maximal heart rate very likely attested near maximal ventilation during the step change. The protocol was also found to be easily performed by children with minimal constraint since the connection to the breathing apparatus was necessary only for a few breaths.…”

Section: Discussionmentioning

confidence: 87%

Down-Regulation of Cough during Exercise Is Less Frequent in Healthy Children than Adults. Role of the Development and/or Atopy?

et al. 2017

View full text Add to dashboard Cite

Cough is typically associated with physical activity in children with asthma, but the characteristics of the relationship between cough and exercise has not been established under physiological conditions. The aim of the study was to describe the effect of exercise on the reflex cough response elicited by a single breath of capsaicin in non-asthmatic children. A group of non-asthmatic adults was studied as reference. Thirty children and 29 adults were recruited. The cough reflex sensitivity to capsaicin was first determined to establish the dose that provokes 5 cough efforts (C5). The number of coughs elicited by C5 (NC5) was then compared at baseline and during a standardized submaximal treadmill exercise. Data are expressed as median (interquartile range). Children and adults showed a significant decrease in NC5 (respectively from 5.0 (4.0–6.0) to 2.5 (2.0–4.0), p < 0.0005 and from 6.0 (5.0–7.0) to 2.0 (0.0–3.0, p < 0.0005). During exercise, NC5 was observed to decrease in all adult subjects, but in only 24/30 children (80%, p = 0.02). A trend for a higher incidence of personal and familial atopy was observed in children that lacked cough down-regulation during exercise compared with other children. It is concluded that the cough reflex response to capsaicin is down regulated by exercise in both children and adults. The effect however is less consistently observed in the former. The difference may reflect maturation of descending inhibitory pathways of the cough reflex, but may also be associated to atopy. The data stress the importance of assessing the time relationship of cough and exercise in questionnaire studies of asthma.

show abstract

Ventilation and Heart Rate Response During Exercise in Normals: Relevance for Rate Variable Pacing

Cited by 35 publications

References 11 publications

Utility of an alternative bicycle commute route of lower proximity to motorised traffic in decreasing exposure to ultra-fine particles, respiratory symptoms and airway inflammation – a structured exposure experiment

Utility of an alternative bicycle commute route of lower proximity to motorised traffic in decreasing exposure to ultra-fine particles, respiratory symptoms and airway inflammation – a structured exposure experiment

Oxygen uptake kinetics during low intensity exercise: relevance for rate adaptive pacemaker programming.

Down-Regulation of Cough during Exercise Is Less Frequent in Healthy Children than Adults. Role of the Development and/or Atopy?

Contact Info

Product

Resources

About